妇女抽烟易患膀胱癌
http://www.100md.com
2001年4月4日
NEW YORK (Reuters Health) - When it comes to bladder cancer, two things have always seemed clear: smokers and men are at heightened risk. But new research shows that, cigarette for cigarette, female smokers are more likely than males to get the disease.
In a study of more than 3,000 adults with and without bladder cancer, researchers found that when smoking habits were comparable, women had a higher risk for the disease than men did. The finding is surprising, investigators say, because bladder cancer, which has long been linked to smoking, is more common among men.
, 百拇医药
``This is not what you'd expect,'' Dr. Ronald K. Ross of the University of Southern California in Los Angeles said in an interview. ``In the US, bladder cancer's been thought of as a disease of white men.''
Ross and his colleagues report the findings in the April 4th issue of the Journal of the National Cancer Institute (news - web sites).
Men get bladder cancer about three times as often as women do, according to the National Cancer Institute. While smoking is a major risk for the disease, it has seemed to have a stronger effect on white males' susceptibility. For example, Ross noted, black men in Los Angeles have higher rates of smoking but lower rates of bladder cancer compared with white men in the area. In this study, he and his colleagues were trying to figure out why smoking affects groups differently.
, 百拇医药
They unexpectedly found that women seem more vulnerable than men to smoking's effects on bladder cancer risk. For example, among smokers who lit up 40 times a day for 40 or more years, women were more than twice as likely as men to develop bladder cancer. According to Ross, women and men may differ in how they process certain cancer-causing compounds in tobacco smoke. Research in lung cancer, he noted, has also suggested that women are more vulnerable to smoking's ill effects.
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The next step, Ross said, is to study what genetic and environmental factors make subgroups of smokers more or less susceptible to bladder cancer.
Besides smoking, workplace exposure to compounds called aromatic amines are linked to bladder cancer. Workers in the rubber, leather, textile and paint industries are among those who face an elevated risk for the disease.
According to Ross, the fact that female smokers seem more likely to get bladder cancer--even though the disease is significantly more common among men--shows that ``something else is going on.'' Researchers, he said, do not yet fully understand how bladder cancer arises.
, 百拇医药
In any case, the finding that women smokers are at especially high risk for bladder cancer provides them with yet another good reason to quit. ``Young women, and especially teenagers, are smoking more than young men,'' Ross said. ``That doesn't bode well for the future.''
SOURCE: Journal of the National Cancer Institute 2001;93:538-545., 百拇医药
In a study of more than 3,000 adults with and without bladder cancer, researchers found that when smoking habits were comparable, women had a higher risk for the disease than men did. The finding is surprising, investigators say, because bladder cancer, which has long been linked to smoking, is more common among men.
, 百拇医药
``This is not what you'd expect,'' Dr. Ronald K. Ross of the University of Southern California in Los Angeles said in an interview. ``In the US, bladder cancer's been thought of as a disease of white men.''
Ross and his colleagues report the findings in the April 4th issue of the Journal of the National Cancer Institute (news - web sites).
Men get bladder cancer about three times as often as women do, according to the National Cancer Institute. While smoking is a major risk for the disease, it has seemed to have a stronger effect on white males' susceptibility. For example, Ross noted, black men in Los Angeles have higher rates of smoking but lower rates of bladder cancer compared with white men in the area. In this study, he and his colleagues were trying to figure out why smoking affects groups differently.
, 百拇医药
They unexpectedly found that women seem more vulnerable than men to smoking's effects on bladder cancer risk. For example, among smokers who lit up 40 times a day for 40 or more years, women were more than twice as likely as men to develop bladder cancer. According to Ross, women and men may differ in how they process certain cancer-causing compounds in tobacco smoke. Research in lung cancer, he noted, has also suggested that women are more vulnerable to smoking's ill effects.
, http://www.100md.com
The next step, Ross said, is to study what genetic and environmental factors make subgroups of smokers more or less susceptible to bladder cancer.
Besides smoking, workplace exposure to compounds called aromatic amines are linked to bladder cancer. Workers in the rubber, leather, textile and paint industries are among those who face an elevated risk for the disease.
According to Ross, the fact that female smokers seem more likely to get bladder cancer--even though the disease is significantly more common among men--shows that ``something else is going on.'' Researchers, he said, do not yet fully understand how bladder cancer arises.
, 百拇医药
In any case, the finding that women smokers are at especially high risk for bladder cancer provides them with yet another good reason to quit. ``Young women, and especially teenagers, are smoking more than young men,'' Ross said. ``That doesn't bode well for the future.''
SOURCE: Journal of the National Cancer Institute 2001;93:538-545., 百拇医药