强大的“狂暴”音乐可以增强安非他明对大脑的损害(下)
&nbps;&nbps;&nbps;&nbps;Mice exposed to loud music and meth in combination also exhibited a much higher incidence of seizures and even death compared with mice in the other groups. While none of the mice died in the unexposed group, "5 of the 40 mice exposed to meth/Prodigy and 4 of the 40 mice exposed to meth/Bach died," she said, as did one of the mice exposed to meth alone.
&nbps;&nbps;&nbps;&nbps;Behaviors in all of the surviving mice appeared to return to normal after the experiments, Morton said. "However, we wanted to see if there were any long-term effects of meth/noise exposure on the (rodents') brains."
&nbps;&nbps;&nbps;&nbps;They dissected the mice brains, looking for signs of gliosis--the proliferation of a certain type of brain cell that Morton described as "a marker for brain damage."
&nbps;&nbps;&nbps;&nbps;All of the mice given meth showed significant signs of gliosis. But while this sign of brain damage disappeared in about 14 days in mice exposed to meth in the "silent" condition, "gliosis in the brains of meth/music treated mice was still high after 2 weeks," Morton said.
&nbps;&nbps;&nbps;&nbps;"Indeed, even 5 weeks later, a persistent gliosis was seen in the brains of mice exposed to meth/Prodigy. Thus, the long-term toxicity of meth appears to be more severe when taken while exposed to loud music," she stated.
&nbps;&nbps;&nbps;&nbps;Of course human neurology is much more complex than that of mice, and the researchers believe that more study in humans is needed before any definite conclusions can be reached.
&nbps;&nbps;&nbps;&nbps;Morton also stressed that the findings " should not be extrapolated to encompass other party drugs such as Ecstasy," although she believes a similar study on the effects of loud music and Ecstasy could be "very interesting."
&nbps;&nbps;&nbps;&nbps;SOURCE: NeuroReport, 2001:12:1-5., http://www.100md.com
&nbps;&nbps;&nbps;&nbps;Behaviors in all of the surviving mice appeared to return to normal after the experiments, Morton said. "However, we wanted to see if there were any long-term effects of meth/noise exposure on the (rodents') brains."
&nbps;&nbps;&nbps;&nbps;They dissected the mice brains, looking for signs of gliosis--the proliferation of a certain type of brain cell that Morton described as "a marker for brain damage."
&nbps;&nbps;&nbps;&nbps;All of the mice given meth showed significant signs of gliosis. But while this sign of brain damage disappeared in about 14 days in mice exposed to meth in the "silent" condition, "gliosis in the brains of meth/music treated mice was still high after 2 weeks," Morton said.
&nbps;&nbps;&nbps;&nbps;"Indeed, even 5 weeks later, a persistent gliosis was seen in the brains of mice exposed to meth/Prodigy. Thus, the long-term toxicity of meth appears to be more severe when taken while exposed to loud music," she stated.
&nbps;&nbps;&nbps;&nbps;Of course human neurology is much more complex than that of mice, and the researchers believe that more study in humans is needed before any definite conclusions can be reached.
&nbps;&nbps;&nbps;&nbps;Morton also stressed that the findings " should not be extrapolated to encompass other party drugs such as Ecstasy," although she believes a similar study on the effects of loud music and Ecstasy could be "very interesting."
&nbps;&nbps;&nbps;&nbps;SOURCE: NeuroReport, 2001:12:1-5., http://www.100md.com