新英格兰医学杂志发表约会迷魂丸研究
美联社消息 研究发现，自美国政府禁止约会迷魂丸GHB的销售后，至少有两人死于GHB的化学衍生物1,4-丁二醇，六人在过去的十年里过量服用这种药物。这些丁二醇服用过量病例都发生在1991年美国食品及药物管理局禁止约会迷魂丸作为非处方药销售以后，去年美国国会还将拥有约会迷魂丸视为是非法行为。该研究结果发表在近期《新英格兰医学杂志》上。
约会迷魂丸GHB，又称r-羟基丁酸盐，在通宵喧闹晚会上很风行。由于该药可以使人失去正常理智容易被人奸污而被称为约会迷魂丸。1,4-丁二醇可以在人体内转化为GHB。人类学家黛博拉·佐撒克博士认为，由于法医和急诊室都不做GHB检测，所以应该还有很多没有上报的服药过量病例。
丁二醇一般作为工业溶剂使用，合成聚亚安酯、斯潘德克斯、化妆用补湿液和某些合法药物。它可以引起人头昏眼花、癫痫发作、昏迷，并可减慢呼吸而有生命危险。而且，还会增强酒精的作用，与其他镇静剂同时服用时更加危险。1996年全世界有500,000公吨1,4--丁二醇被使用。
, 百拇医药
但《GHB─天然的情绪兴奋剂》一书的作者丁沃德博士认为，这一份研究报告是对GHB有偏见的人的攻击。丁沃德曾在多宗GHB案子中作辩方证人。
Study Examines Drug Overdoses
At least two people have died from a chemical cousin of GHB and six others have overdosed in the decade since the government banned the sale of the ``date-rape drug,‘‘ a study found.
The overdoses took place in Minnesota, Texas and Florida and were blamed on 1,4-butanediol, which turns to GHB in the body.
, 百拇医药
Butanediol is used as an industrial solvent and is also included in supplements sold under names such as Thunder Nectar, InnerG and Zen.
More such overdoses have almost certainly occurred but have gone unreported, in part because many coroners and emergency rooms do not test for GHB, said medical anthropologist Deborah L. Zvosec, a Ph.D. who led the study published in Thursday‘s New England Journal of Medicine (news - web sites).
, 百拇医药 Butanediol can cause dizziness, seizures and coma, and can slow breathing to dangerous levels. It can intensify alcohol‘s effects and is also said to be more dangerous when taken with other depressant drugs.
The butanediol overdoses all occurred after the Food and Drug Administration (news - web sites) banned over-the-counter sales of GHB in 1991. Last year, Congress also made possession of GHB illegal.
GHB, or gamma hydroxybutyrate, is sometimes used at all-night rave parties. It is known as a date-rape drug for its ability to incapacitate people and leave them vulnerable to sexual assault.
, http://www.100md.com
Dr. Ward Dean, author of a book titled ``GHB - The Natural Mood Enhancer‘‘ and defense witness in a number of GHB cases, said the journal study is another attack by people who are biased against the drug.
``This would almost be funny if it wasn‘t so tragic - that this article is going to be published in the New England Journal of Medicine and so many people are going to believe it,‘‘ he said.
Dean said some people mentioned in the report had been taking supplements inappropriately.
Butanediol is used to make polyurethane, Spandex, moisturizers and legal drugs. About 500,000 metric tons of 1,4-butanediol were used worldwide in 1996, according to SRI Consulting Inc., http://www.100md.com
约会迷魂丸GHB，又称r-羟基丁酸盐，在通宵喧闹晚会上很风行。由于该药可以使人失去正常理智容易被人奸污而被称为约会迷魂丸。1,4-丁二醇可以在人体内转化为GHB。人类学家黛博拉·佐撒克博士认为，由于法医和急诊室都不做GHB检测，所以应该还有很多没有上报的服药过量病例。
丁二醇一般作为工业溶剂使用，合成聚亚安酯、斯潘德克斯、化妆用补湿液和某些合法药物。它可以引起人头昏眼花、癫痫发作、昏迷，并可减慢呼吸而有生命危险。而且，还会增强酒精的作用，与其他镇静剂同时服用时更加危险。1996年全世界有500,000公吨1,4--丁二醇被使用。
, 百拇医药
但《GHB─天然的情绪兴奋剂》一书的作者丁沃德博士认为，这一份研究报告是对GHB有偏见的人的攻击。丁沃德曾在多宗GHB案子中作辩方证人。
Study Examines Drug Overdoses
At least two people have died from a chemical cousin of GHB and six others have overdosed in the decade since the government banned the sale of the ``date-rape drug,‘‘ a study found.
The overdoses took place in Minnesota, Texas and Florida and were blamed on 1,4-butanediol, which turns to GHB in the body.
, 百拇医药
Butanediol is used as an industrial solvent and is also included in supplements sold under names such as Thunder Nectar, InnerG and Zen.
More such overdoses have almost certainly occurred but have gone unreported, in part because many coroners and emergency rooms do not test for GHB, said medical anthropologist Deborah L. Zvosec, a Ph.D. who led the study published in Thursday‘s New England Journal of Medicine (news - web sites).
, 百拇医药 Butanediol can cause dizziness, seizures and coma, and can slow breathing to dangerous levels. It can intensify alcohol‘s effects and is also said to be more dangerous when taken with other depressant drugs.
The butanediol overdoses all occurred after the Food and Drug Administration (news - web sites) banned over-the-counter sales of GHB in 1991. Last year, Congress also made possession of GHB illegal.
GHB, or gamma hydroxybutyrate, is sometimes used at all-night rave parties. It is known as a date-rape drug for its ability to incapacitate people and leave them vulnerable to sexual assault.
, http://www.100md.com
Dr. Ward Dean, author of a book titled ``GHB - The Natural Mood Enhancer‘‘ and defense witness in a number of GHB cases, said the journal study is another attack by people who are biased against the drug.
``This would almost be funny if it wasn‘t so tragic - that this article is going to be published in the New England Journal of Medicine and so many people are going to believe it,‘‘ he said.
Dean said some people mentioned in the report had been taking supplements inappropriately.
Butanediol is used to make polyurethane, Spandex, moisturizers and legal drugs. About 500,000 metric tons of 1,4-butanediol were used worldwide in 1996, according to SRI Consulting Inc., http://www.100md.com