要宝宝健康，室内清洁很重要
路透社纽约健康消息 要宝宝健康，室内清洁很重要。美国哈佛大学公共卫生学院的唐纳德·米尔顿博士及其同事的最新研究发现，室内灰尘中细菌内毒素使婴儿哮喘发作的危险性增加了33%。家居家灰尘中存在的细菌内毒素是一种气道刺激物。室内灰尘中细菌内毒素愈多，婴儿的哮喘发作愈常见。研究人员认为， 一岁以内婴儿的哮喘发作与细菌内毒素有关。
研究人员指出，事实上，环境中这些内毒素无所不在，包括房子里的灰尘，也含有不少细菌内毒素。但目前还不知道哪些内毒素可导致哮喘恶化。
研究人员对近500名易患哮喘的婴儿家中灰尘的内毒素含量进行测定，对婴儿出生后头三个月及一岁生日前哮喘发作时的灰尘水平进行了比较。结果发现，在养狗的家庭、以及灰尘中含有较高水平的蟑螂蛋白的家庭中，内毒素水平含量最高。排除了吸烟及家中养狗等其它已知的危险因素，起居室含有高水平的内毒素使婴儿哮喘发作的危险性增加了33%。研究人员强调，内毒素的水平还与婴儿哮喘反复发作有一定的关系。
, 百拇医药
研究发现，对于有过敏或哮喘家族病史的婴儿，内毒素可以增加哮喘发作的危险，还会促使喘息持续性发作。内毒素增加哮喘发作的危险是独立存在的，与下呼吸道感染无关。下呼吸道感染是引起婴儿哮喘的最危险因素之一。
研究人员的结论是，“至于这些婴儿是生来(遗传)就对内毒素敏感，还是或多或少容易得哮喘，目前还不知道。”
来源：《美国呼吸及急救护理医学杂志》
Wheezing in Infants Linked to Bacterial Toxin
NEW YORK (Reuters Health) - Dust has long been the bane of meticulous housekeepers and now there is another reason to banish it from the home. According to researchers, wheezing during the first year of life is more common in infants whose homes have high levels of bacterial endotoxin, an airway irritant that can be present in common house dust.
, 百拇医药
Endotoxin is virtually everywhere in the environment, including house dust, but studies have not clearly shown that endotoxin causes asthma to get worse, says Dr. Donald Milton from Harvard School of Public Health in Boston, Massachusetts, and associates.
The authors measured endotoxin levels from dust in the homes of nearly 500 infants who were predisposed to asthma. The researchers compared the dust levels during the first three months of life with reports of wheezing before the infants‘ first birthdays.
, 百拇医药
The findings are published in the February issue of the American Journal of Respiratory and Critical Care Medicine.
Endotoxin levels were highest in the homes of families with a dog, and in homes with higher levels of cockroach protein in the dust, the report indicates.
High levels of endotoxin in the living room brought a 33% increase in the risk of wheezing during the first year of life even after adjusting for other known risk factors such as smoking and the presence of a dog, the authors report.
, 百拇医药
There was also a weak link between the level of endotoxin and the risk of repeated wheezing episodes during the first year of life, the researchers note.
``Endotoxin is associated with increased risk of wheeze, and may promote persistent wheezing during the first year of life among children with a family history of allergy or asthma,‘‘ the authors write. ``The risks were independent of the effect of lower respiratory infection--one of the strongest risk factors for wheeze in infancy.‘‘
``It remains to be determined,‘‘ they conclude, ``whether these infants are genetically more susceptible to endotoxin exposure or are at greater or lesser risk of developing asthma.‘‘
SOURCE: American Journal of Respiratory and Critical Care Medicine, 百拇医药
研究人员指出，事实上，环境中这些内毒素无所不在，包括房子里的灰尘，也含有不少细菌内毒素。但目前还不知道哪些内毒素可导致哮喘恶化。
研究人员对近500名易患哮喘的婴儿家中灰尘的内毒素含量进行测定，对婴儿出生后头三个月及一岁生日前哮喘发作时的灰尘水平进行了比较。结果发现，在养狗的家庭、以及灰尘中含有较高水平的蟑螂蛋白的家庭中，内毒素水平含量最高。排除了吸烟及家中养狗等其它已知的危险因素，起居室含有高水平的内毒素使婴儿哮喘发作的危险性增加了33%。研究人员强调，内毒素的水平还与婴儿哮喘反复发作有一定的关系。
, 百拇医药
研究发现，对于有过敏或哮喘家族病史的婴儿，内毒素可以增加哮喘发作的危险，还会促使喘息持续性发作。内毒素增加哮喘发作的危险是独立存在的，与下呼吸道感染无关。下呼吸道感染是引起婴儿哮喘的最危险因素之一。
研究人员的结论是，“至于这些婴儿是生来(遗传)就对内毒素敏感，还是或多或少容易得哮喘，目前还不知道。”
来源：《美国呼吸及急救护理医学杂志》
Wheezing in Infants Linked to Bacterial Toxin
NEW YORK (Reuters Health) - Dust has long been the bane of meticulous housekeepers and now there is another reason to banish it from the home. According to researchers, wheezing during the first year of life is more common in infants whose homes have high levels of bacterial endotoxin, an airway irritant that can be present in common house dust.
, 百拇医药
Endotoxin is virtually everywhere in the environment, including house dust, but studies have not clearly shown that endotoxin causes asthma to get worse, says Dr. Donald Milton from Harvard School of Public Health in Boston, Massachusetts, and associates.
The authors measured endotoxin levels from dust in the homes of nearly 500 infants who were predisposed to asthma. The researchers compared the dust levels during the first three months of life with reports of wheezing before the infants‘ first birthdays.
, 百拇医药
The findings are published in the February issue of the American Journal of Respiratory and Critical Care Medicine.
Endotoxin levels were highest in the homes of families with a dog, and in homes with higher levels of cockroach protein in the dust, the report indicates.
High levels of endotoxin in the living room brought a 33% increase in the risk of wheezing during the first year of life even after adjusting for other known risk factors such as smoking and the presence of a dog, the authors report.
, 百拇医药
There was also a weak link between the level of endotoxin and the risk of repeated wheezing episodes during the first year of life, the researchers note.
``Endotoxin is associated with increased risk of wheeze, and may promote persistent wheezing during the first year of life among children with a family history of allergy or asthma,‘‘ the authors write. ``The risks were independent of the effect of lower respiratory infection--one of the strongest risk factors for wheeze in infancy.‘‘
``It remains to be determined,‘‘ they conclude, ``whether these infants are genetically more susceptible to endotoxin exposure or are at greater or lesser risk of developing asthma.‘‘
SOURCE: American Journal of Respiratory and Critical Care Medicine, 百拇医药