番茄红素治男性不育
路透社新德里健康消息 印度新德里的全印医学科学研究所发现:番茄红素(Lycopene)有助提高男人的生育力。番茄红素是一种天然的抗氧化剂,存在于西瓜、葡萄、西红柿及一些贝类动物中。
研究人员让30名年龄在23到45岁之间的不育男子每日口服两次番茄红素,每次2毫克,持续服药三个月后测量他们的精子浓度,活动力和形状。结果发现,他们的精子浓度和精子活力的改善显著,具有统计学意义。2/3患者的精子浓度有所升高,几乎3/4患者的精子活力上升,63%患者的精子细胞形状有了改进。其中6名患者的妻子在该实验后怀孕了。
番茄红素在男性睾丸中的浓度较高,但在患有不育症的男性体内的浓度却较低。目前的研究发现,口服番茄红素对于不明原因引起的不育症的治疗似乎是有效的,但在确定用于临床治疗之前,还需要较大规模的临床随机对照试验。
该研究由印度加桑帕医药有限公司资助,研究结果发表在今年印度泌尿医生协会在那格浦尔召开的大会上。
Antioxidant Said to Help Fight Infertility in Men
NEW DELHI (Reuters Health) - Lycopene, a naturally occurring antioxidant found in watermelon, grapes, tomatoes and some shellfish, seems to help improve fertility in men, studies conducted at the All India Institute of Medical Sciences in New Delhi suggest.
Researchers Rajeev Kumar and N. P. Gupta orally administered 2 milligrams of lycopene twice daily for 3 months to 30 infertile men aged 23 to 45, and measured the concentration, activity and shape of their sperm.
``We found that improvement in sperm concentration and (activity) was statistically significant,‘‘ Gupta said. Sperm concentration improved in 20 patients. Almost three in four patients displayed improved sperm activity and 63% showed improvement in sperm cell shape.
There were six pregnancies after the trial, he added.
``Lycopene...is found in high concentrations in male testes and lower levels of lycopene are found in infertile males,‘‘ Gupta told Reuters Health.
``Oral lycopene therapy does seem to have a positive role in the management of infertility of unknown causes,‘‘ he added. ‘‘However, larger randomized controlled trials are essential before definitive therapeutic guidelines can be laid down.‘‘
The results were first announced at the Nagpur meeting of the Indian Association of Urologists held in January. The trials were sponsored by the Indian drug company Jagsonpal Pharmaceuticals, Ltd., http://www.100md.com
研究人员让30名年龄在23到45岁之间的不育男子每日口服两次番茄红素,每次2毫克,持续服药三个月后测量他们的精子浓度,活动力和形状。结果发现,他们的精子浓度和精子活力的改善显著,具有统计学意义。2/3患者的精子浓度有所升高,几乎3/4患者的精子活力上升,63%患者的精子细胞形状有了改进。其中6名患者的妻子在该实验后怀孕了。
番茄红素在男性睾丸中的浓度较高,但在患有不育症的男性体内的浓度却较低。目前的研究发现,口服番茄红素对于不明原因引起的不育症的治疗似乎是有效的,但在确定用于临床治疗之前,还需要较大规模的临床随机对照试验。
该研究由印度加桑帕医药有限公司资助,研究结果发表在今年印度泌尿医生协会在那格浦尔召开的大会上。
Antioxidant Said to Help Fight Infertility in Men
NEW DELHI (Reuters Health) - Lycopene, a naturally occurring antioxidant found in watermelon, grapes, tomatoes and some shellfish, seems to help improve fertility in men, studies conducted at the All India Institute of Medical Sciences in New Delhi suggest.
Researchers Rajeev Kumar and N. P. Gupta orally administered 2 milligrams of lycopene twice daily for 3 months to 30 infertile men aged 23 to 45, and measured the concentration, activity and shape of their sperm.
``We found that improvement in sperm concentration and (activity) was statistically significant,‘‘ Gupta said. Sperm concentration improved in 20 patients. Almost three in four patients displayed improved sperm activity and 63% showed improvement in sperm cell shape.
There were six pregnancies after the trial, he added.
``Lycopene...is found in high concentrations in male testes and lower levels of lycopene are found in infertile males,‘‘ Gupta told Reuters Health.
``Oral lycopene therapy does seem to have a positive role in the management of infertility of unknown causes,‘‘ he added. ‘‘However, larger randomized controlled trials are essential before definitive therapeutic guidelines can be laid down.‘‘
The results were first announced at the Nagpur meeting of the Indian Association of Urologists held in January. The trials were sponsored by the Indian drug company Jagsonpal Pharmaceuticals, Ltd., http://www.100md.com
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