治肠癌肝转移 开刀效果好
路透社纽约健康消息 近期《外科档案》发表的一项新研究显示，结肠直肠癌肝转移的病人如果接受外科手术治疗，会有更高的存活机会。
该研究负责人美国伯明翰阿拉巴马大学的外科肿瘤医生马丁·J·赫斯林博士研究了174名结肠癌肝转移病人后发现，只有做了手术的病人的生存期可以超过5年。植入直接向肝释放化疗药物的泵的病人平均生存32个月，而那些肿瘤不能通过外科手术去除的病人的平均存活期只有三个月。
结肠直肠癌肝转移病人可以通过冰冻或者用微波“灼烧”的办法来治疗，也可用一个移植入人体内的泵直接把化疗药送到肝，或采用常规化疗或外科手术。
医生们通常认为，对转移癌病人施行外科手术会有很大的危险，包括大出血，感染和肝功能衰竭等，因而往往选择其它疗法如化疗等。当然，在某些情况下这是恰当的。然而在其它情况下，外科手术会给病人提供更多的治愈机会。
, 百拇医药
赫斯林博士建议对孤立的结肠直肠癌肝转移病人应该积极考虑做手术。不过，他强调，并不是所有的病人都是适合做手术的。因此，结肠直肠转移癌病人应当由一个包括各学科的医生小组会诊决定最适当的治疗方法。
Surgery May Be Best Way to Treat Liver Tumors
NEW YORK (Reuters Health) - Patients with colorectal cancer that has spread to the liver may have the best chance of survival if their disease is treated surgically, a new report suggests.
Doctors are often concerned about the risks of surgery for these patients and have instead opted for other treatments such as chemotherapy, lead author Dr. Martin J. Heslin told Reuters Health. Risks of surgery include bleeding, infection and liver failure.
, 百拇医药
But in Heslin‘s study of 174 patients with colon cancer that had spread to the liver, those who had surgery survived for 70 months, on average. Only the patients who had the surgery survived for longer than 5 years. Those treated with an implanted pump that delivered chemotherapy drugs directly to the liver lived for 32 months, while those whose tumors could not be removed surgically lived for an average of 3 months, according to the report in the March issue of Archives of Surgery.
, http://www.100md.com
``We recommend an aggressive approach to the surgical management of patients with isolated colorectal hepatic metastases,‘‘ said Heslin, a surgical oncologist from the University of Alabama, Birmingham. ``In years past, many physicians...have been concerned with the safety of surgery and have recommended chemotherapy alone. In some cases this is appropriate, however, in other cases surgical resection (removal) would give the patient a greater chance of cure.‘‘
, 百拇医药 Colorectal cancer that has spread to the liver can also be treated by freezing or ``cooking‘‘ the tumor with microwaves, delivering chemotherapy directly to the liver with an implanted pump, regular chemotherapy or surgery, he explained.
Heslin stressed that not all patients are candidates for surgery, and recommended that all patients with metastatic colorectal cancer be evaluated by a multidisciplinary team of doctors to determine the most appropriate treatment., 百拇医药
该研究负责人美国伯明翰阿拉巴马大学的外科肿瘤医生马丁·J·赫斯林博士研究了174名结肠癌肝转移病人后发现，只有做了手术的病人的生存期可以超过5年。植入直接向肝释放化疗药物的泵的病人平均生存32个月，而那些肿瘤不能通过外科手术去除的病人的平均存活期只有三个月。
结肠直肠癌肝转移病人可以通过冰冻或者用微波“灼烧”的办法来治疗，也可用一个移植入人体内的泵直接把化疗药送到肝，或采用常规化疗或外科手术。
医生们通常认为，对转移癌病人施行外科手术会有很大的危险，包括大出血，感染和肝功能衰竭等，因而往往选择其它疗法如化疗等。当然，在某些情况下这是恰当的。然而在其它情况下，外科手术会给病人提供更多的治愈机会。
, 百拇医药
赫斯林博士建议对孤立的结肠直肠癌肝转移病人应该积极考虑做手术。不过，他强调，并不是所有的病人都是适合做手术的。因此，结肠直肠转移癌病人应当由一个包括各学科的医生小组会诊决定最适当的治疗方法。
Surgery May Be Best Way to Treat Liver Tumors
NEW YORK (Reuters Health) - Patients with colorectal cancer that has spread to the liver may have the best chance of survival if their disease is treated surgically, a new report suggests.
Doctors are often concerned about the risks of surgery for these patients and have instead opted for other treatments such as chemotherapy, lead author Dr. Martin J. Heslin told Reuters Health. Risks of surgery include bleeding, infection and liver failure.
, 百拇医药
But in Heslin‘s study of 174 patients with colon cancer that had spread to the liver, those who had surgery survived for 70 months, on average. Only the patients who had the surgery survived for longer than 5 years. Those treated with an implanted pump that delivered chemotherapy drugs directly to the liver lived for 32 months, while those whose tumors could not be removed surgically lived for an average of 3 months, according to the report in the March issue of Archives of Surgery.
, http://www.100md.com
``We recommend an aggressive approach to the surgical management of patients with isolated colorectal hepatic metastases,‘‘ said Heslin, a surgical oncologist from the University of Alabama, Birmingham. ``In years past, many physicians...have been concerned with the safety of surgery and have recommended chemotherapy alone. In some cases this is appropriate, however, in other cases surgical resection (removal) would give the patient a greater chance of cure.‘‘
, 百拇医药 Colorectal cancer that has spread to the liver can also be treated by freezing or ``cooking‘‘ the tumor with microwaves, delivering chemotherapy directly to the liver with an implanted pump, regular chemotherapy or surgery, he explained.
Heslin stressed that not all patients are candidates for surgery, and recommended that all patients with metastatic colorectal cancer be evaluated by a multidisciplinary team of doctors to determine the most appropriate treatment., 百拇医药