肝移植临床化学指标实验诊断价值
肝移植;实验诊断;化学指标,刘爱兵,李玲,郝钦芳,王海燕,通讯作者:,Laboratorydiagnosticvaluesofclinicalchemicalmarkersinlivertransplantation,Ai-BingLiu,LingLi,Qin
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刘爱兵, 李玲, 郝钦芳, 王海燕, 武警总医院检验科 北京市 100039
通讯作者: 刘爱兵, 100039, 北京市海淀区永定路69号, 武警总医院检验科. doctor_liuaibing@yahoo.com.cn
电话: 010-88276749
收稿日期: 2006-10-20 接受日期: 2007-02-13
Laboratory diagnostic values of clinical chemical markers in liver transplantation
Ai-Bing Liu, Ling Li, Qin-Fang Hao, Hai-Yan Wang
Ai-Bing Liu, Ling Li, Qin-Fang Hao, Hai-Yan Wang,Department of Laboratory Medicine, General Hospital of Chinese People’s Armed Police Forces, Beijing 100039, China
Correspondence to:Ai-Bing Liu, Department of Laboratory Medicine, General Hospital of Chinese People’s Armed Police Forces, 69 Yongding Road, Haidian District, Beijing 100039, China. doctor_liuaibing@yahoo.com.cn
Received:2006-10-20 Accepted:2007-02-13
Abstract
AIM: To explore the laboratory diagnostic values of twelve markers in liver transplantation.
METHODS: The documents of 98 cases received liver transplantation were analyzed. According to the standard of discharge diagnosis, the cases were classified into 3 groups: cured group, complication group and death group. The changes and characteristics of 12 indexes were analyzed, including alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyltranspeptidase (GGT), alkaline phosphatase (ALP), aldolase (ALD), leucine aminopeptidase (LAP), glutamate dehydrogenase (GLDH), cholinesterase (CHE), prealbumin (PA), total biliary acid (TBA), total bilirubin (TB), and direct bilirubin (DB).
RESULTS: ALT, AST, ALD and GLDH were more sensitive for the ischemia/reperfusion injury following liver transplantation. Transplanted liver survival and its function in secreting bile and excreting were predicted by TB, DB and TBA, and the proteins metabolism was reflected by PA and CHE. The acute rejection was indicated by ALT, GGT, ALP, TB and DB. ALT, AST, GGT, TB and DB were specific for medical reaction in anti-rejection ......
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