胃上皮异型增生的新概念
胃上皮异型增生;胃癌前病变;胃癌;诊断标准;维也纳分类系统,李凯,唐志鹏,戴彦成,唐志鹏,通讯作者:,Updateddiagnosticcriteriaongastricepithelialdyspalsia,KaiLi,Zhi-PengTang,Yan-Chen
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李凯, 唐志鹏, 戴彦成, 上海中医药大学附属龙华医院消化内科 上海市 200032
唐志鹏, 博士, 主任医师, 主要从事中医药治疗、胃肠病及肝病方面的研究.
通讯作者: 唐志鹏, 200032, 上海市, 上海中医药大学附属龙华医院消化内科. zhipengtang@sohu.com
电话: 021-64385700-3925
收稿日期: 2007-02-01 接受日期: 2007-03-06
Updated diagnostic criteria on gastric epithelial dyspalsia
Kai Li, Zhi-Peng Tang, Yan-Cheng Dai
Kai Li, Zhi-Peng Tang, Yan-Cheng Dai,Department of Gastroenterology, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
Correspondence to:Zhi-Peng Tang, Department of Gastroenterology, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China. zhipengtang@sohu.com
Received:2007-02-01 Accepted:2007-03-06
Abstract
Large discrepancies exist between Eastern and Western countries in the diagnostic criteria for gastric epithelial dysplasia. With the purpose of a worldwide-accepted terminology and classification of precancerous lesions, Padova and Vienna classifications are established and reach a consensus that epithelial dysplasia is the earliest visible manifestation of neoplasia and the stage at which invasion has not yet occurred. So the primary term ‘dysplasia’ is confusing and misleading as gastric precancerous lesion. With more insight into dysplasia, new directions will be found to explore the pathogenesis, reversibility and therapy of dysplasia.
Key Words: Gastric epithelial dyspalsia; Gastric precancerous lesion; Gastric cancer; Diagnostic criteria; Vienna classification
Li K, Tang ZP, Dai YC. Updated diagnositic criteria on gastric epithelial dyspalsia. Shijie Huaren Xiaohua Zazhi 2007;15(11):1181-1184
摘要
关于异型增生的诊断标准, 在东西方国家的胃肠病学术界存在着很大差异, 曾一度导致诊断上的混乱. 鉴于此, 国际上制定了帕达瓦和维也纳新分类系统, 对异型增生的诊断标准提出全新的概念, 明确将高级别胃上皮异型增生作为胃癌最早期的镜下可见阶段, 只是尚未发生浸润. 因此, 异型增生作为胃癌前病变这一描述已不再准确. 深化对胃上皮异型增生的认识与理解, 加强对其形成机制、可逆性和治疗方面的研究, 是当前重要的研究课题 ......
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