肝脏炎性肌纤维母细胞瘤研究进展
炎性肌纤维母细胞瘤;肝脏,付雪琼,林军,通讯作者:,Advancementofresearchoninflammatorymyofibroblastictumoroftheliver,Xue-QiongFu,JunLin,Correspondenceto
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付雪琼, 林军, 武汉大学中南医院消化内科, 武汉大学医学院消化系疾病研究中心 湖北省武汉市 430071
通讯作者: 林军, 430071, 湖北省武汉市东湖路169号, 武汉大学中南医院消化内科, 武汉大学医学院消化系疾病研究中心. linjun64@yahoo.com.cn
收稿日期: 2006-10-07 接受日期: 2007-01-31
Advancement of research on inflammatory myofibroblastic tumor of the liver
Xue-Qiong Fu, Jun Lin
Xue-Qiong Fu, Jun Lin,Department of Gastroenterology, Zhongnan Hospital; Research Center of Digestive Diseases, Wuhan University School of Medicine, Wuhan 430071, Hubei Province, China
Correspondence to:Jun Lin, Department of Gastroenterology, Zhongnan Hospital; Research Center of Digestive Diseases, Wuhan University School of Medicine, Wuhan 430071, Hubei Province, China. linjun64@yahoo.com.cn
Received:2006-10-07 Accepted:2007-01-31
Abstract
Inflammatory myofibroblastic tumor (IMT) is a mesenchymal neoplasm composed of transformed myofibroblastic spindle cells with infiltration of a large number of inflammatory cells and/or lymphocytes. The etiology of IMT remains unknown. IMT occurs at various sites and often affects young adults and children. IMT of the liver mostly arises in the right lobe of liver. Biopsy, computed tomography (CT) and magnetic resonance imaging (MRI) are beneficial to diagnosis and differential diagnosis. Vimentin, smooth muscle actin (SMA), muscle-specific actin (MSA) are often positive by immunohistochemistry. The prognosis of most patients is favorable after surgery. In this article, we reviewed the overseas and domestic literatures and summarized the advancement of research on the IMT of the liver about etiology, pathogenesis, clinical presentations, imaging feature, histological appearance, immunohistochemical and electron microscopic feature, diagnosis, differential diagnosis and therapy.
Key Words: Inflammatory myofibroblastic tumor; Liver
Fu XQ, Lin J. Advancement of research on inflammatory myofibroblastic tumor of the liver. Shijie Huaren Xiaohua Zazhi 2007;15(11):1257-1260 ......
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