利福昔明在消化疾病中的临床应用进展
利福昔明;憩室病;肠内细菌过度生长;炎症性肠病;幽门螺杆菌,崔东来,姚希贤,陈卫,崔东来,通讯作者:,ClinicalapplicationprogressofRifaximininthetreatmentofdigestivediseases,D
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崔东来, 姚希贤, 河北医科大学第二医院消化内科 河北省石家庄市 050000
陈卫, 河北体育学院医院内科 河北省石家庄市 050041
崔东来, 1985年毕业于南通医学院, 现任河北医科大学第二医院主任医师, 博士研究生, 主要从事慢性胃病、慢性肝病的研究工作, 发表研究论文40篇, 主编、参编著作6部.
通讯作者: 崔东来, 050000, 河北省石家庄市, 河北医科大学第二医院消化内科. liver369@126.com
电话: 0311-87222301
收稿日期: 2007-02-25 接受日期: 2007-03-17
Clinical application progress of Rifaximin in the treatment of digestive diseases
Dong-Lai Cui, Wei Chen, Xi-Xian Yao
Dong-Lai Cui, Xi-Xian Yao,Department of Gastroenterology, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China
Wei Chen,Department of Internal Medicine, Hospital of Hebei institute of Physical Education, Shijiazhuang 050041, Hebei Province, China
Correspondence to:Dong-Lai Cui, Department of Gastroenterology, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China. liver369@126.com
Received:2007-02-25 Accepted:2007-03-17
Abstract
Rifaximin, a derivative of rifamycin, has high antibacterial activity on various kinds of Gram-positive and -negative aerobes and anaerobes, and it is a new drug in the treatment of giardiasis. Rifaximin is not easy to be absorbed after oral administration, and mild systemic adverse reaction is the main characteristic. Recently, Rifaximin has been widely and effectively used in the therapy of many diseases related to intestinal bacterial infection such as hepatic encephalopathy, diverticular disease, overgrowth of intestinal bacteria, inflammatory bowel disease (IBD) and H pylori infection. The above advances were reviewed in the present article.
Key Words: Rifaximin; Diverticular disease; Over-growth of intestinal bacteria; Inflammatory bowel disease; Helicobacter pylori
Cui DL, Chen W, Yao XX. Clinical application progress of Rifaximin in the treatment of digestive diseases. Shijie Huaren Xiaohua Zazhi 2007;15(13):1457-1462 ......
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