三种抗病毒治疗方法对慢性乙型肝炎患者生活质量的影响
慢性乙型肝炎;抗病毒治疗;SF36问卷;生活质量,王艳,于岩岩,斯崇文,陈新月,韩忠厚,陈宇萍,通讯作者:,AssessmentonlifequalityofpatientswithchronichepatitisBafterthreety
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王艳, 于岩岩, 斯崇文, 北京大学第一医院感染疾病科 北京市 100034
陈新月, 北京市佑安医院特需科 北京市 100069
韩忠厚, 秦皇岛市第三人民医院肝病科 河北省秦皇岛市 066001
陈宇萍, 保定市传染病医院肝病科 河北省保定市 071000
王艳, 2002年北京大学感染疾病科临床博士, 主治医师, 主要从事慢性肝病的诊治.
北京市科委重大项目, No. H020920020690
北京大学211工程资助项目, No. 91000-246156054
通讯作者: 于岩岩, 100034, 北京市西城区西什库大街8号, 北京大学第一医院感染疾病科. yyy@bjmu.edu.cn
电话: 010-66551122-2362
收稿日期: 2007-02-27 接受日期: 2007-03-17
Assessment on life quality of patients with chronic hepatitis B after three types of antiviral treatmentYan Wang, Yan-Yan Yu, Chong-Wen Si, Xin-Yue Chen, Zhong-Hou Han, Yu-Ping Chen
Yan Wang, Yan-Yan Yu, Chong-Wen Si, Department of Infectious Diseases, Peking University First Hospital, Beijing 100034, China
Xin-Yue Chen, Department of Special Service, Beijing You’an Hospital, Beijing 100069, China
Zhong-Hou Han, Department of Hepatology, Qinhuangdao Third Hospital, Qinhuangdao 066001, Hebei Province, China
Yu-Ping Chen, Department of Hepatology, Baoding Hospital for Infectious Diseases, Baoding 071000, Hebei Province, China
Supported by the Important Item of Beijing Science Committee, No. H020920020690, Peking University “211” Project Item, No. 91000-246156054
Correspondence to: Yan-Yan Yu, Department of Infectious Diseases, Peking University First Hospital, 8 Xishiku Street, Xicheng District, Beijing 100034, China. yyy@bjmu.edu.cn
Received: 2007-02-27 Accepted: 2007-03-17
Abstract
AIM: To assess the life quality of patients with chronic hepatitis B after different approaches to antiviral treatment.
METHODS: A total of 143 patients were randomly divided into group A, B and C, received lamivudine plus interferon-α2b sequential therapy, lamivudine and interferon-α2b therapy, respectively. The life quality of the 143 patients with chronic hepatitis B was assessed by the quality of life questionnaire (SF-36 in Chinese) ......
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