原发性胆汁性肝硬化患者自身抗体测定的意义
原发性胆汁性肝硬化;抗线粒体抗体;抗核抗体;抗中性粒细胞胞质抗体;抗髓过氧化酶抗体;间接免疫荧光法;酶联免疫测定,刘宁,谭立明,曹莉萍,李华,蔡莉莉,董叶,徐承云,通讯作者:,Clinicalapplicationofautoantibodiesinp
 |
| 第1页 |
参见附件(841KB，4页)。
刘宁, 谭立明, 曹莉萍, 李华, 蔡莉莉, 南昌大学第二附属医院检验科 江西省南昌市 330006
董叶, 南昌大学第二附属医院消化内科 江西省南昌市 330006
徐承云, 南昌大学第二附属医院肾内科 江西省南昌市330006
通讯作者: 谭立明, 330006, 江西省南昌市民德路1号, 南昌大学第二附属医院检验科. yuuje@sohu.com
收稿日期: 2007-03-15 修回日期: 2007-07-18
Clinical application of autoantibodies in patients with primary biliary liver cirrhosis
Ning Liu, Li-Ming Tan, Ye Dong, Li-Ping Cao, Hua Li, Li-Li Cai, Cheng-Yun Xu
Ning Liu, Li-Ming Tan, Li-Ping Cao, Hua Li, Li-Li Cai, Department of Laboratory, the Second Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China
Ye Dong, Department of Gastroenterology, the Second Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China
Cheng-Yun Xu, Department of Nephrology, the Second Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China
Correspondence to: Li-Ming Tan, Department of Laboratory, the Second Affiliated Hospital of Nanchang University, 1 Minde Road, Nanchang 330006, Jiangxi Province, China. yuuje@sohu.com
Received: 2007-03-15 Revised: 2007-07-18
Abstract
AIM: To study the clinical significance of autoantibodies in patients with primary biliary liver cirrhosis (PBC).
METHODS: The patients with PBC (n = 52), non-PBC (n = 202) and healthy physical examination people (n = 40) were examined in this research. Autoantibodies against cell nuclei (ANA), smooth muscle (SMA), mitochondria (AMA), heart cells, skeletal muscle, parietal cells, double-stranded DNA, live-kidney microsomes, soluble antigen, and neutrophil cytoplasm were detected by indirect immunofluorescence assay, and anti-myeloperoxidase (MPO) autoantibodies were detected by enzyme-linked immunosorbent assay.
RESULTS: AMA positive rate was 88.5% (46/52), which was the highest positive rate in PBC patients. ANA positive rate was 71.2% (37/52) in PBC patients ......
您现在查看是摘要介绍页，详见PDF附件(841KB，4页)。