幽门螺杆菌阳性的疣状胃炎治疗112例
疣状胃炎;幽门螺杆菌,刘洁,于皆平,通讯作者:,TreatmentofverrucousgastritiswithHelicobacterpyloriinfection:ananalysisof112cases,JieLiu,Jie-PingYu,C
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刘洁, 于皆平, 湖北省武汉市省人民医院消化内科 湖北省武汉市 430060
通讯作者: 刘洁, 430060, 湖北省武汉市省人民医院消化内科. ginger512@gmail.com
电话: 027-82915189
收稿日期: 2007-03-27 修回日期: 2007-08-09
Treatment of verrucous gastritis with Helicobacter pylori infection: an analysis of 112 cases
Jie Liu, Jie-Ping Yu
Jie Liu, Jie-Ping Yu,Department of Gastroenterology, People’s Hospital, Wuhan 430060, Hubei Province, China
Correspondence to:Jie Liu, Department of Gastroenterology, People’s Hospital, Wuhan 430060, Hubei Province, China. ginger512@gmail.com
Received:2007-03-27 Revised:2007-08-09
Abstract
AIM: To investigate the relationship between Helicobacter pylori and verrucous gastritis.
METHODS: One hundred and twelve patients with verrucous gastritis diagnosed by endoscopy were randomly divided into two groups. All patients had H pylori infection. Patients in group A were treated with rabeprazole, amoxicillin and clarithromycin; and patients in group B were treated with rabeprazole and placebo. Treatment duration was 1 wk in both groups. After 1 mo, the clinical symptoms, endoscopic manifestations and H pylori infection were characterized.
RESULTS: There was a significant difference (89.3% vs 75.0%; 91.1% vs 76.8%; P < 0.05) in clinical symptoms and endoscopic manifestations between group A and group B. All the patients that were clearly in good condition were followed up at 6 mo, and the relapse rate in group A was lower than that in group B (P < 0.05). All relapsing patients were infected with H pylori and had a positive rate of H pylori of 100%. In the non-relapsing patients, the positive rate of H pylori was 37.7%.
CONCLUSION: There was a close relationship between H pylori and verrucous gastritis.
Key Words: Verrucous gastritis; Helicobactor pylori
Liu J, Yu JP. Treatment of verrucous gastritis with Helicobacter pylori infection: an analysis of 112 cases ......
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