妊娠急性脂肪肝组织的体液免疫反应
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郑智勇, 王 晨, 曲利娟, 杨才生, 曾 玲, 冯昌银
妊娠急性脂肪肝;免疫球蛋白;补体;免疫组化,郑智勇,王晨,曲利娟,曾玲,冯昌银,杨才生,通讯作者:,Humoralimmunityreactionsinthelivertissuesofpatientswithacutefattyliverduringpregn
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郑智勇, 王晨, 曲利娟, 曾玲, 冯昌银, 福建医科大学福总临床学院/南京军区福州总医院病理科 福建省福州市 350025
杨才生, 福建医科大学福总临床学院/南京军区福州总医院肝病内科 福建省福州市 350025
通讯作者: 郑智勇, 350025, 福建省福州市西二环北路156号, 南京军区福州总医院病理科. zzy@public.fz.fj.cn
电话: 0591-83717703 传真: 0591-83717703
收稿日期: 2007-06-28 修回日期: 2007-11-02
Humoral immunity reactions in the liver tissues of patients with acute fatty liver during pregnancy
Zhi-Yong Zheng, Chen Wang, Li-Juan Qu, Cai-Sheng Yang, Ling Zeng, Chang-Yin Feng
Zhi-Yong Zheng, Chen Wang, Li-Juan Qu, Ling Zeng, Chang-Yin Feng, Department of Pathology, Fuzhou General Hospital of Nanjing Military Command, Fuzong Clinical School of Fujian Medical University, Fuzhou 350025, Fujian Province, China
Cai-Sheng Yang, Department of Hepatopathy, Fuzhou General Hospital of Nanjing Military Command, Fuzong Clinical School of Fujian Medical University, Fuzhou 350025, Fujian Province, China
Correspondence to: Dr. Zhi-Yong Zheng, Department of Pathology, Fuzhou General Hospital of Nanjing Military Command, Fuzong Clinical School of Fujian Medical University, 156 Xi’erhuanbei Road, Fuzhou 350025, Fujian Province, China. zzy@public.fz.fj.cn
Received: 2007-06-28 Revised: 2007-11-02
Abstract
AIM: To observe whether humoral immunity reactions participate in acute fatty liver during pregnancy (AFLP).
METHODS: The deposition of all kinds of immunoglobulin and complements was observed in three cases of AFLP by immunohistochemical staining.
RESULTS: In cases 1 and 2, many rough particles of IgG, C1q or C4c were deposited in hepatic sinusoidal endothelial cells, while Kupffer cells swallowed many positive particles of IgG, IgM, IgA and C1q. Different amounts of C1q and C4d were deposited in the portal area and vessel endothelial cells, respectively in case 3, many IgG, IgM and IgA molecules were deposited in hepatic sinusoidal endothelial cells and portal area, but very few complements were deposited ......
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