胃癌侵犯胃裸区与CD34、VEGF、VEGF-C表达的关系及临床意义
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程 鑫, 韩 明, 张仕状, 董 鹏, 曲林涛
胃癌;胃裸区;CD34;血管内皮生长因子;淋巴管内皮生长因子,程鑫,张仕状,董鹏,曲林涛,韩明,通讯作者:,Clinicalsignificanceandrelationshipbetweengastricbareareain
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程鑫, 张仕状, 董鹏, 曲林涛, 潍坊医学院医学影像学系 山东省潍坊市 261042
韩明, 潍坊医学院基础医学教学部 山东省潍坊市 261042
国家自然科学基金资助项目, No. 30772716
通讯作者: 程鑫, 261042, 山东省潍坊市, 潍坊医学院医学影像学系. chengxin131008@yahoo.com.cn
电话: 0536-2602681
收稿日期: 2007-09-03 修回日期: 2007-11-28
Clinical significance and relationship between gastric bare area involved in gastric carcinoma and expression of CD34, VEGF and VEGF-C
Xin Cheng, Ming Han, Shi-Zhuang Zhang, Peng Dong, Lin-Tao Qu
Xin Cheng, Shi-Zhuang Zhang, Peng Dong, Lin-Tao Qu, Department of Medical Imaging, Weifang Medical College, Weifang 261042, Shandong Province, China
Ming Han, Department of Basic Medicine, Weifang Medical College, Weifang 261042, Shandong Province, China
Supported by: National Natural Science Foundation of China, No. 30772716
Correspondence to: Xin Cheng, Department of Medical Imaging, Weifang Medical College, Weifang 261042, Shandong Province, China. chengxin131008@yahoo.com.cn
Received: 2007-09-13 Revised: 2007-11-28
Abstract
AIM: To detect the expression of CD34, vascular endothelial growth factor (VEGF) and vascular endothelial growth factor C (VEGF-C) in gastric carcinoma, and to investigate the clinical significance and relationship between the gastric bare area (GBA) involved in gastric carcinoma and expression of CD34, VEGF and VEGF-C.
METHODS: Seventy-two cases of gastric carcinoma were divided into GBA involved and non-involved groups. Expression of CD34, VEGF and VEGF-C was detected by immunohistochemistry.
RESULTS: In gastric carcinoma, there was no significant difference in the expression of VEGF (27/32 vs 28/40), CD34(61.67 ± 21.33 vs 60.79 ± 22.04) or VEGF-C (23/32 vs 26/40) in GBA involved and non-involved groups. In proximal gastric carcinoma, there was no significant difference in the expression of VEGF (23/30 vs 6/9), CD34 (62 ......
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