稳心颗粒对老年心律失常患者24小时心电图检测结果的影响.pdf
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率最高 , (11/ 12) 。选择性合成的多肽
TK1与胰岛素受体具有较高亲和力 , Kd
值达到4152× 108
L/M, 可以作为潜在的
肝癌靶向多肽 , 值得进一步研究。多肽
TL (Gln Ile HIs Pro His Ala Pro) 的生物
学特性有待进一步研究。
5 参考文献:
[ 1 ] Gaponigro F. Rationale and clinical valida2
tion of epidermal growth factor receptor as a
target in the treatment of head and neck can2
cer [ J ] . Anticancer Drugs , 2004 , 15
(4) : 311 - 320.
[ 2 ] Apte SM, Bucana CD , Killion JJ , et al .
Expression of platelet - derived growth factor
and activated receptor in clinical specimens
of epithelial ovarian cancer and ovarian car2
cinoma cell lines [ J ] . Gynecol Oncol ,2004 , 93 (1) : 78 - 86.
[ 3 ] Lorenzo GD , Bianco R , Tortora G, et al .
Involvement of growth factor receptors of the
epidermal growth factor receptor family in
prostate cancer development and progression
to androgen independence [ J ] . Clin
Prostate Cancer , 2003 , 2 (1) : 50 - 7.
[ 4 ] Underiner TL , Ruggeri B , Gingrich DE.
Development of vascular endothelial growth
factor receptor (VEGFR) kinase inhibitors
as anti - angiogenic agents in cancer therapy
[J ] . Curr Med Chem, 2004 , 11 ( 6 ) :
731 - 45.
[ 5 ] Tiseo M, Loprevite M, Ardizzoni A. Epi2
dermal growth factor receptor inhibitors : a
new prospective in the treatment of lung can2
cer [J ] . Curr Med Chem Anti - Canc A2
gents , 2004 , 4 (2) : 139 - 48.
[ 6 ] Wu J , Richer J , Horwitz KB , et al . Pro2
gestin - dependent induction of vascular en2
dothelial growth factor in human breast can2
cer cells : preferential regulation by proges2
terone receptor B [J ] . Cancer Res , 2004 ,64 (6) : 2238 - 44.
[ 7 ] Thomas M. Epidermal growth factor receptor
tyrosine kinase inhibitors : application in non
- small cell lung cancer [ J ] . Cancer
Nurs , 2003 , 26 (6 Suppl) : 21S - 25S.
[ 8 ] Ellis LM, Hoff PM. Targeting the epider2
mal growth factor receptor : an important in2
cremental step in the battle against colorectal
cancer [ J ] . J Clin Oncol , 2004 , 22
(7) : 1177 - 9.
[ 9 ] Yao HQ , Peng Y, Zhong ZZ , et al . As2
sociation of the expressions of platelet - de2
rived growth factor receptor and c - Fos with
the biological characteristics of bladder can2
cer [J ] . Di Yi Jun Yi Da Xue Xue Bao ,2004 , 24 (2) : 177 - 9.
[10] Luo YQ , Wu MC , Cong WM. Gene ex2
pression of hepatocyte growth factor and its
receptor in HCC and nontumorous liver tis2
sues [J ] . World J Gastroenterol , 1999 , 5
(2) : 119 - 121.
[11 ] Wang R , Ferrell LD , Faouzi S , et al .
Activation of the Met receptor by cell attach2
ment induces and sustains hepatocellular car2
cinomas in transgenic mice [J ] . J Cell Bi2
ol , 2001 , 153 (5) : 1023 - 34.
[12 ] Jia WD , Xu GL , Xu RN , et al . Oc2
treotide acts as an antitumor angiogenesis
compound and suppresses tumor growth in
nude mice bearing human hepatocellular car2
cinoma xenografts [J ] . J Cancer Res Clin
Oncol , 2003 , 129 (6) : 327 - 34.
[13 ] Rumi MA , Sato H , Ishihara S , et al .
Peroxisome proliferator - activated receptor
gamma ligand - induced growth inhibition of
human hepatocellular carcinoma [J ] . Br J
Cancer , 2001 , 84 (12) : 1640 - 7.
[14 ] Yoong KF , McNab G, Hubscher SG, et
al . Vascular adhesion protein - 1 and ICAM ......
TK1与胰岛素受体具有较高亲和力 , Kd
值达到4152× 108
L/M, 可以作为潜在的
肝癌靶向多肽 , 值得进一步研究。多肽
TL (Gln Ile HIs Pro His Ala Pro) 的生物
学特性有待进一步研究。
5 参考文献:
[ 1 ] Gaponigro F. Rationale and clinical valida2
tion of epidermal growth factor receptor as a
target in the treatment of head and neck can2
cer [ J ] . Anticancer Drugs , 2004 , 15
(4) : 311 - 320.
[ 2 ] Apte SM, Bucana CD , Killion JJ , et al .
Expression of platelet - derived growth factor
and activated receptor in clinical specimens
of epithelial ovarian cancer and ovarian car2
cinoma cell lines [ J ] . Gynecol Oncol ,2004 , 93 (1) : 78 - 86.
[ 3 ] Lorenzo GD , Bianco R , Tortora G, et al .
Involvement of growth factor receptors of the
epidermal growth factor receptor family in
prostate cancer development and progression
to androgen independence [ J ] . Clin
Prostate Cancer , 2003 , 2 (1) : 50 - 7.
[ 4 ] Underiner TL , Ruggeri B , Gingrich DE.
Development of vascular endothelial growth
factor receptor (VEGFR) kinase inhibitors
as anti - angiogenic agents in cancer therapy
[J ] . Curr Med Chem, 2004 , 11 ( 6 ) :
731 - 45.
[ 5 ] Tiseo M, Loprevite M, Ardizzoni A. Epi2
dermal growth factor receptor inhibitors : a
new prospective in the treatment of lung can2
cer [J ] . Curr Med Chem Anti - Canc A2
gents , 2004 , 4 (2) : 139 - 48.
[ 6 ] Wu J , Richer J , Horwitz KB , et al . Pro2
gestin - dependent induction of vascular en2
dothelial growth factor in human breast can2
cer cells : preferential regulation by proges2
terone receptor B [J ] . Cancer Res , 2004 ,64 (6) : 2238 - 44.
[ 7 ] Thomas M. Epidermal growth factor receptor
tyrosine kinase inhibitors : application in non
- small cell lung cancer [ J ] . Cancer
Nurs , 2003 , 26 (6 Suppl) : 21S - 25S.
[ 8 ] Ellis LM, Hoff PM. Targeting the epider2
mal growth factor receptor : an important in2
cremental step in the battle against colorectal
cancer [ J ] . J Clin Oncol , 2004 , 22
(7) : 1177 - 9.
[ 9 ] Yao HQ , Peng Y, Zhong ZZ , et al . As2
sociation of the expressions of platelet - de2
rived growth factor receptor and c - Fos with
the biological characteristics of bladder can2
cer [J ] . Di Yi Jun Yi Da Xue Xue Bao ,2004 , 24 (2) : 177 - 9.
[10] Luo YQ , Wu MC , Cong WM. Gene ex2
pression of hepatocyte growth factor and its
receptor in HCC and nontumorous liver tis2
sues [J ] . World J Gastroenterol , 1999 , 5
(2) : 119 - 121.
[11 ] Wang R , Ferrell LD , Faouzi S , et al .
Activation of the Met receptor by cell attach2
ment induces and sustains hepatocellular car2
cinomas in transgenic mice [J ] . J Cell Bi2
ol , 2001 , 153 (5) : 1023 - 34.
[12 ] Jia WD , Xu GL , Xu RN , et al . Oc2
treotide acts as an antitumor angiogenesis
compound and suppresses tumor growth in
nude mice bearing human hepatocellular car2
cinoma xenografts [J ] . J Cancer Res Clin
Oncol , 2003 , 129 (6) : 327 - 34.
[13 ] Rumi MA , Sato H , Ishihara S , et al .
Peroxisome proliferator - activated receptor
gamma ligand - induced growth inhibition of
human hepatocellular carcinoma [J ] . Br J
Cancer , 2001 , 84 (12) : 1640 - 7.
[14 ] Yoong KF , McNab G, Hubscher SG, et
al . Vascular adhesion protein - 1 and ICAM ......
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