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Central Nervous System Control of Movement
XING, GUOGANG(ÐϹú¸Õ), MD. Ph.D.
±±¾©´óѧ Éñ¾¿ÆѧÑо¿Ëù
Neuroscience Research Institute, Peking University
Email address: ggxing@bjmu.edu.cn
Introduction
* ÉúÃüÔÚÓÚÔ˶¯......
* Ô˶¯ÊǶ¯Îïάϵ¸öÌåÉú´æºÍÖÖ×å·±ÑܵĻù±¾¹¦ÄÜÖ®Ò»
How does a coordinated movement achieved ?
The motor control hierarchy have three levels
* The highest level- strategy
> Represented by the association areas of neocortex and basal ganglia of the forebrain
> Is concerned with strategy:
?a The goal of the movement and the movement strategy that best achieves the goal
The motor control hierarchy have three levels
* The middle level-tactics
> Represented by the motor cortex and cerebellum
> Is concerned with tactics
- The sequences of muscle contractions
? Arranged in space and time
? Required to smoothly and accurately achieve the strategic goal
The motor control hierarchy have three levels
* The lowest level- execution
> Represented by the brain stem and spinal cord
> Is concerned with execution
- Action of the motor neuron and interneuron pools that generate the goal-directed movement and make any necessary adjustments of posture
Overview
* ¼¹ËèÄÚµÄ"ÏÂÔ˶¯Éñ¾Ôª(Lower neurons)?¡À¡ê?³ýÁËÊܵ½¼¹ËèÄÚ¾Ö²¿»·Â·µÄÓ°ÏìÍ⣬»¹Êܵ½´óÄÔƤ²ãÔ˶¯Çø¼°ÄÔ¸ÉÖÐÐí¶à"ÉÏÔ˶¯Éñ¾Ôª(Upper neurons)?¡ÀµÄÖ§ÅäºÍе÷
* »ùµ×Éñ¾½ÚºÍСÄÔÔòÏòÄÇЩÉÏÔ˶¯Éñ¾ÔªÌṩijÖָоõ¡¢ÈÏÖª»ò¸ÐÐÔµÄÐÅÏ¢£¬Ê¹Ô˶¯¸ü¼Ó¾«È·ºÍе÷
ÿ
Part 1
Spinal Control of Movement
Introduction
* "running around like a chicken with its head cut off"
* The rhythmic movements could be elicited in the hind legs of cats and dogs long after their spinal cords had been severed from the rest of the central nervous system
-Charles Sherington & Graham Brown (English)
- The importance of circuitry within the spinal cord for the coordinated control of movements
Spinal circuitry control of movement
Spinal motor neurons
* Alpha motor neurons
Innervate skeletal muscle (extrafusal muscle) ......
Central Nervous System Control of Movement
XING, GUOGANG(ÐϹú¸Õ), MD. Ph.D.
±±¾©´óѧ Éñ¾¿ÆѧÑо¿Ëù
Neuroscience Research Institute, Peking University
Email address: ggxing@bjmu.edu.cn
Introduction
* ÉúÃüÔÚÓÚÔ˶¯......
* Ô˶¯ÊǶ¯Îïάϵ¸öÌåÉú´æºÍÖÖ×å·±ÑܵĻù±¾¹¦ÄÜÖ®Ò»
How does a coordinated movement achieved ?
The motor control hierarchy have three levels
* The highest level- strategy
> Represented by the association areas of neocortex and basal ganglia of the forebrain
> Is concerned with strategy:
?a The goal of the movement and the movement strategy that best achieves the goal
The motor control hierarchy have three levels
* The middle level-tactics
> Represented by the motor cortex and cerebellum
> Is concerned with tactics
- The sequences of muscle contractions
? Arranged in space and time
? Required to smoothly and accurately achieve the strategic goal
The motor control hierarchy have three levels
* The lowest level- execution
> Represented by the brain stem and spinal cord
> Is concerned with execution
- Action of the motor neuron and interneuron pools that generate the goal-directed movement and make any necessary adjustments of posture
Overview
* ¼¹ËèÄÚµÄ"ÏÂÔ˶¯Éñ¾Ôª(Lower neurons)?¡À¡ê?³ýÁËÊܵ½¼¹ËèÄÚ¾Ö²¿»·Â·µÄÓ°ÏìÍ⣬»¹Êܵ½´óÄÔƤ²ãÔ˶¯Çø¼°ÄÔ¸ÉÖÐÐí¶à"ÉÏÔ˶¯Éñ¾Ôª(Upper neurons)?¡ÀµÄÖ§ÅäºÍе÷
* »ùµ×Éñ¾½ÚºÍСÄÔÔòÏòÄÇЩÉÏÔ˶¯Éñ¾ÔªÌṩijÖָоõ¡¢ÈÏÖª»ò¸ÐÐÔµÄÐÅÏ¢£¬Ê¹Ô˶¯¸ü¼Ó¾«È·ºÍе÷
ÿ
Part 1
Spinal Control of Movement
Introduction
* "running around like a chicken with its head cut off"
* The rhythmic movements could be elicited in the hind legs of cats and dogs long after their spinal cords had been severed from the rest of the central nervous system
-Charles Sherington & Graham Brown (English)
- The importance of circuitry within the spinal cord for the coordinated control of movements
Spinal circuitry control of movement
Spinal motor neurons
* Alpha motor neurons
Innervate skeletal muscle (extrafusal muscle) ......
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