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编号:176398
糖脉康对2型糖尿病患者尿微白蛋白排泄率作用的临床研究
http://www.100md.com 2002年5月25日 新药网
     迟家敏

    (卫生部北京医院内分泌科,北京 100730)

    [摘要] 目的:研究糖脉康对2型糖尿病患者尿微白蛋白排泄率(UAER)的作用。方法:104例2型糖尿病患者进行随机及自身对照开放研究,分为治疗组74例和对照组30例,其中治疗组口服糖脉康颗粒5g,tid,对照组30例口服安慰剂1袋,tid,疗程6个月。观察治疗前和治疗开始后3,6个月UAER的变化。结果:与治疗前比较,糖脉康可明显地降低2型糖尿病患者3个月和6个月的UAER(均P<0.01),与对照组比较,也有明显差异(分别P<0.05和P<0.01)。结论:糖脉康可降低2型糖病患者的UAER。

    [关键词]糖脉康;2型糖尿病;尿微白蛋白排泄率

    Clinical study on the effects of Tangmaikang upon urinary microalbumin
, http://www.100md.com
    excretive rate in patients with type 2 diabetes mellitus

    CHI Jia-min

    (Department of Endocrinology,Beijing Hospital,Beijing 100730,China)

    [Abstract] Objective:To study the effecs of Tangmaikang(a kind of Chinese traditional medicine ) on urinary microalbumin excretive rate(UAER) in patients with type 2 diabetes mellitus(DM).Methods:104 patients with type 2 DM were divided into two groups in a ramdom and open study :74 cases of treatment group given Tangmaikang 5g, and 30 cases of control group given placebo 1 packet,po,tid for 6 months.The UAER were observed at treament before and after 3th and 6th month.Results:In the treatment group,the UAER had reduced in treatment 3th and 6th month compared with the treatment before(P<0.01),there were significant difference compared with control group(P<0.05 and P<0.01,respectively).Conclusion:UAER were reduced by Tangmaikang in patients with type 2 DM.
, 百拇医药
    [Key words] Tangmaikang;type 2 diabetes mellitus;urinary microalbumin excretive rate

    [参考文献]

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, 百拇医药
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    [4] UK Prospective Diabetes Study Group.Intensive bloodglucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes(UKPDS 33)[J]. Lancet,1998,352∶837-853.
, 百拇医药
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    (收稿日期:2001-07-31 修回日期:2001-08-30), http://www.100md.com