http://www.100md.com
2004年9月27日
丁祖荣 宋冬雷 周良辅 李士其 医用生物力学 2000年第3期第15卷 论著
摘 要：硬脑膜及替代物的抗膨出特性在无骨支撑的颅骨缺损重建中有重要意义。本文根据骨缺损时硬脑膜在脑压作用下的弯曲变形特点，引入抗膨出特性参数：初始变形指数和蠕变指数。用该参数为硬脑膜及其替代物排序，说明新鲜人硬脑膜为最佳抗膨出材料，冻干人硬脑膜为最佳替代品，而牛心包人工膜、硅橡胶膜和涤纶膜均不适宜作抗膨出材料。测量表明冻干人硬脑膜可近似按各向同性材料处理，颞肌筋膜和颅骨膜则表现出各向异性特征。本文提出的方法和结果可临床参考。
A STUDY OF ANTI-PROTRUDING PROPERTIES OF DURA AND ITS SUBSTITUFES
ding Zurong(Department of Engineering Mechanics, Shanghai Jiaotong University, Shanghai 200030)
song Donglei,Zhou Liangfu(Department of Neurosurgery, Shanghai Huashan Hospital, Shanghai 200040)
Abstract：The study of anti-protruding properties of dura and its substitutes is important to reconstnlction of skull defecfs. The parameters of anti-protruding properties of dura and its substitutes are introduced on the basis of constant creep solution of the dural deflection under the constant intracranial pressure. Dura and its Substitutes are arranged in order to the parameters: fresh human dura is the best anti-protruding material, lyophilized human dura is the best substitute, and artificial membrane of bovine cardiac valve, silicone rubber and terylene are unsuitable for use as anti-protruding material. The measurements showed that dura is isotropic approximately, which temporalis myofascia and pericranium are anisotropic.
Keywords：Dural Reconstruction, lyophilized dura, dura substitutes, anti-protruding properties.参考文献：
[1]吴彦桥，任光.颅底肿瘤术后缺损的重建和修复材料研究进展.中国耳鼻咽喉颅底外科杂志1995；1：56.
[2]丁祖荣，宋冬雷，李士其等.硬脑膜及其替代物的蠕变特性.上海交通大学学报1998；32：93.
[3]Galford J E，Mcelhaney JH.A viscoelastic study of scalp brain and dura.J Biomechanics 1970；3：211.
[4]朱兴华，施德广，董心等.人体硬脑膜、大脑镰和小脑镰的力学试验研究.吉林工业大学学报1988；9：46.
[5]丁祖荣，宋冬雷，周良辅等.硬脑膜稳态蠕变膨出研究.上海交通大学学报2000；34.
[6]杨立，于彦铮，余建伟.生物瓣膜性能的研究——硬脑膜的形态结构及脉动流测试.人工心膜瓣膜的脉动流测试及生物材料的研究报告1991；87～95.
[7]周晓平，赵盂尧，岳志健等.冻干人体硬脑膜移植的实验研究和临床应用.中华实验外科杂志1992；9：4.
摘 要：硬脑膜及替代物的抗膨出特性在无骨支撑的颅骨缺损重建中有重要意义。本文根据骨缺损时硬脑膜在脑压作用下的弯曲变形特点，引入抗膨出特性参数：初始变形指数和蠕变指数。用该参数为硬脑膜及其替代物排序，说明新鲜人硬脑膜为最佳抗膨出材料，冻干人硬脑膜为最佳替代品，而牛心包人工膜、硅橡胶膜和涤纶膜均不适宜作抗膨出材料。测量表明冻干人硬脑膜可近似按各向同性材料处理，颞肌筋膜和颅骨膜则表现出各向异性特征。本文提出的方法和结果可临床参考。
A STUDY OF ANTI-PROTRUDING PROPERTIES OF DURA AND ITS SUBSTITUFES
ding Zurong(Department of Engineering Mechanics, Shanghai Jiaotong University, Shanghai 200030)
song Donglei,Zhou Liangfu(Department of Neurosurgery, Shanghai Huashan Hospital, Shanghai 200040)
Abstract：The study of anti-protruding properties of dura and its substitutes is important to reconstnlction of skull defecfs. The parameters of anti-protruding properties of dura and its substitutes are introduced on the basis of constant creep solution of the dural deflection under the constant intracranial pressure. Dura and its Substitutes are arranged in order to the parameters: fresh human dura is the best anti-protruding material, lyophilized human dura is the best substitute, and artificial membrane of bovine cardiac valve, silicone rubber and terylene are unsuitable for use as anti-protruding material. The measurements showed that dura is isotropic approximately, which temporalis myofascia and pericranium are anisotropic.
Keywords：Dural Reconstruction, lyophilized dura, dura substitutes, anti-protruding properties.参考文献：
[1]吴彦桥，任光.颅底肿瘤术后缺损的重建和修复材料研究进展.中国耳鼻咽喉颅底外科杂志1995；1：56.
[2]丁祖荣，宋冬雷，李士其等.硬脑膜及其替代物的蠕变特性.上海交通大学学报1998；32：93.
[3]Galford J E，Mcelhaney JH.A viscoelastic study of scalp brain and dura.J Biomechanics 1970；3：211.
[4]朱兴华，施德广，董心等.人体硬脑膜、大脑镰和小脑镰的力学试验研究.吉林工业大学学报1988；9：46.
[5]丁祖荣，宋冬雷，周良辅等.硬脑膜稳态蠕变膨出研究.上海交通大学学报2000；34.
[6]杨立，于彦铮，余建伟.生物瓣膜性能的研究——硬脑膜的形态结构及脉动流测试.人工心膜瓣膜的脉动流测试及生物材料的研究报告1991；87～95.
[7]周晓平，赵盂尧，岳志健等.冻干人体硬脑膜移植的实验研究和临床应用.中华实验外科杂志1992；9：4.