郑克立 吴培根 朱兰英 中华泌尿外科杂志 1999年第8期第20卷

    【摘要】 目的 探讨尸体肾移植术后人巨细胞病毒(HCMV)病的防治。 方法 应用HCMV-Ag试验诊断HCMV感染，对1 150例尸体肾移植进行回顾性分析。 结果 治疗组：1989年9月～1997年4月共1 050例, HCMV病45例,治愈30例,死亡15例；预防组：1997年5月～1998年5月共100例，活动性HCMV感染42例，由于进行了预防性治疗，无1例HCMV病发生和因HCMV感染而死亡。 结论 HCMV-Ag试验可以早期诊断活动性HCMV感染，指导HCMV病的有效治疗；对活动性HCMV感染积极进行预防性治疗，能显著减少HCMV病的发生。

    Prophylaxis of HCMV disease for patients undenwent cadaveric renal transplantation

    ZHENG Keli，WU Peigen，ZHU Lanying，et al.

    The First Affiliated Hospital, Sun Yatsen University of Medical Sciences,Guangzhou 510080

    【Abstract】 Objective To study the efficacy of prophylactic therapy of HCMV disease for patients underwent cadaveric renal transplantation. Methods HCMV infection has been detected by means of antigenemia test in 1 150 patients underwent cadaveric renal transplantation and prophylactic management has bee instituted in 42 patients before renal transplantation. Results From Sep.1989 to Apr.1997,HCMV disease was detected after renal transplantation in 45 patients out of 1 050. 30 have been cured of the disease while mortslity occurred in 15 in spite of treatment.From May 1997 to May 1998,active HCMV infection was detected before renal transplantation in 42 out of 100 and appropriate treatment was instituted before transplantation as a prophylactic measure.No HCMV disease occurred after the renal transplantation and there has been no mortatlity because of HCMV disease. Conclusions Detection and treatment of HCMV infection before renal transplantation is very beneficial to the patients and is highly recommended. ......