不稳定性心绞痛危险因素及临床分型与冠状动脉病变的关系(摘要)
作者：吴桂平(研究生) 曾定尹 齐国先 谢兆丽(进修医生)
单位：辽宁省沈阳市，中国医科大学第一临床学院 心内科(110001)
关键词：
目的 目的：本研究通过冠状动脉造影了解不稳定性心绞痛(UAP)冠状动脉病变与临床分型及危险因素之间的关系。
方法：对诊断为UAP并进行冠状动脉造影的77例患者进行分析。
结果：UAP患者冠状动脉病变支数在各年龄组有显著差异(P<0.01),伴有高血压、高血脂、糖尿病及吸烟者冠状动脉病变较重与不伴有上述危险因素的患者相比有显著差异(P<0.05)，初发劳累型心绞痛单支病变与多支病变相比有极显著差异(P<0.01)，初发劳累型心绞痛与恶化劳累型心绞痛、梗塞后心绞痛、混合型心绞痛单支病变相比有显著差异(P<0.05)。梗塞后心绞痛次全或完全闭塞明显增多(51.09%)与其他各型心绞痛相比均有显著差异(P<0.05)，此型血栓的检出率较高(14.8%)。恶化劳累型、梗塞后心绞痛及混合型心绞痛，其冠状动脉病变，以多支病变、偏心型、复杂型病变及B、C型病变发生率较高，其与初发劳累型、变异型、静息型心绞痛相比有显著差异(P<0.05)。
, 百拇医药
结论：①不稳定性心绞痛患者冠状动脉病变随着年龄增长，多支病变逐渐增加，伴有高血压、高血脂、糖尿病及吸烟者冠状动脉病变较重。②初发劳累型心绞痛单支病变、同心型及A型病变多见。③梗塞后心绞痛冠状动脉血管次全或完全闭塞多见。④恶化劳累型心绞痛、梗塞后心绞痛及混合型心绞痛冠状动脉病变，多表现为多支、偏心型、复杂型及B、C型病。
Correlation between Coronary Lesions and Clinical Manifestations in Unstable Angina (Abstract)
Department of Cardiovascular Medicine, The First Clinical College of China Medical University, Shenyang (110001), Liaoning
Wu Guiping, Zeng Dingyin, Qi Guoxian, et al.
, 百拇医药
Objective: To investigate the correlation between coronary arter lesions and clinical types and risk factors in patient with unstable angina.
Methods: Clinical data of 77 cases unstable angina undergone selective coronary angiography were analyzed.
Results: Type B and C were more common in unstable angina patient with risk factors (p<0.05). There was correlation between multi-vessels lesions and ages (p<0.01). Single-vessel disease was more in patients with recent onset effort angina than in other groups (p<0.01). Subtotal or total occlusions were more frequently found in post infarction angina (p<0.05). Coronary thrombi were more common in patient with post infarction angina. Eccentric and complex lesions were more common in accelerated effort angina and post infarction and mixed angina than in other three types of angina (p<0.05). Multi-vessels lesions and eccentric lesions and complex lesions occured more frequently.
, 百拇医药
Conclusion: ① Coronary lesions were more serious in unstabale angina patients with risk factors, there was correlation between multi-vessels lesions and ages. ② Recent onset effort angina is more in single-vessel and type A lesion. ③ Subtotal or total occlusions occured more frequently in patients with post infarction angina than other types of angina. ④ Multi-vessels, eccentric and complex lesions, and type B and C occureed more commonly in patients with accelerated efforanginat, post infarction angina and mixed angina., 百拇医药
单位：辽宁省沈阳市，中国医科大学第一临床学院 心内科(110001)
关键词：
目的 目的：本研究通过冠状动脉造影了解不稳定性心绞痛(UAP)冠状动脉病变与临床分型及危险因素之间的关系。
方法：对诊断为UAP并进行冠状动脉造影的77例患者进行分析。
结果：UAP患者冠状动脉病变支数在各年龄组有显著差异(P<0.01),伴有高血压、高血脂、糖尿病及吸烟者冠状动脉病变较重与不伴有上述危险因素的患者相比有显著差异(P<0.05)，初发劳累型心绞痛单支病变与多支病变相比有极显著差异(P<0.01)，初发劳累型心绞痛与恶化劳累型心绞痛、梗塞后心绞痛、混合型心绞痛单支病变相比有显著差异(P<0.05)。梗塞后心绞痛次全或完全闭塞明显增多(51.09%)与其他各型心绞痛相比均有显著差异(P<0.05)，此型血栓的检出率较高(14.8%)。恶化劳累型、梗塞后心绞痛及混合型心绞痛，其冠状动脉病变，以多支病变、偏心型、复杂型病变及B、C型病变发生率较高，其与初发劳累型、变异型、静息型心绞痛相比有显著差异(P<0.05)。
, 百拇医药
结论：①不稳定性心绞痛患者冠状动脉病变随着年龄增长，多支病变逐渐增加，伴有高血压、高血脂、糖尿病及吸烟者冠状动脉病变较重。②初发劳累型心绞痛单支病变、同心型及A型病变多见。③梗塞后心绞痛冠状动脉血管次全或完全闭塞多见。④恶化劳累型心绞痛、梗塞后心绞痛及混合型心绞痛冠状动脉病变，多表现为多支、偏心型、复杂型及B、C型病。
Correlation between Coronary Lesions and Clinical Manifestations in Unstable Angina (Abstract)
Department of Cardiovascular Medicine, The First Clinical College of China Medical University, Shenyang (110001), Liaoning
Wu Guiping, Zeng Dingyin, Qi Guoxian, et al.
, 百拇医药
Objective: To investigate the correlation between coronary arter lesions and clinical types and risk factors in patient with unstable angina.
Methods: Clinical data of 77 cases unstable angina undergone selective coronary angiography were analyzed.
Results: Type B and C were more common in unstable angina patient with risk factors (p<0.05). There was correlation between multi-vessels lesions and ages (p<0.01). Single-vessel disease was more in patients with recent onset effort angina than in other groups (p<0.01). Subtotal or total occlusions were more frequently found in post infarction angina (p<0.05). Coronary thrombi were more common in patient with post infarction angina. Eccentric and complex lesions were more common in accelerated effort angina and post infarction and mixed angina than in other three types of angina (p<0.05). Multi-vessels lesions and eccentric lesions and complex lesions occured more frequently.
, 百拇医药
Conclusion: ① Coronary lesions were more serious in unstabale angina patients with risk factors, there was correlation between multi-vessels lesions and ages. ② Recent onset effort angina is more in single-vessel and type A lesion. ③ Subtotal or total occlusions occured more frequently in patients with post infarction angina than other types of angina. ④ Multi-vessels, eccentric and complex lesions, and type B and C occureed more commonly in patients with accelerated efforanginat, post infarction angina and mixed angina., 百拇医药