血生化指标与高脂血症中医虚实证型的关系
唐荣德，罗治华，蒋三员，杨劲松，李应时，刘社炎，郭爱群(广东省江门市新会中医院，广东 江门 529100)
【摘要】 目的：探讨高脂血症患者血脂、血糖(Glu)、尿酸(UA)和C反应蛋白(CRP)等指标变化与中医虚实辨证分型的关系。方法：353例高脂血症患者按虚实辨证分为虚证、实证和虚实夹杂证，检测各证型患者血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、Glu、UA和CRP，并比较各证型检测结果在证型之间相互的变化。结果：3个证型患者TC、TG、LDL-C、HDL-C和CRP的变化均为实证>虚实夹杂证>虚证，Glu为虚证>虚实夹杂证>实证，UA为虚证>实证>虚实夹杂证。TC和TG水平在高脂血症虚证属于轻度升高，在虚实夹杂证属于中度升高，在实证属于重度升高。结论：7个指标与高脂血症虚实证型均有不同程度的关系，利用这些指标可从虚、实和虚实夹杂这三大方面区分高脂血症。
【关键词】 高脂血症；中医证型；血脂；血糖；尿酸
Relationship between blood biochemical indexes and types of deficiency or excess syndromes(虚实证型) of traditional Chinese medicine in cases with hyperlipidemia
TANG Rong-de, LUO Zhi-hua, JIANG San-yuan, YANGJin-song, LI Ying-shi, LIU She-yan, GUO Ai-qun.
Xinhui Hospital of Traditional Chinese Medicine, Jiangmen 529100, Guangdong, China
【Abstract】 Objective： To explore the changes of blood lipids, blood glucose(Glu), uric acid (UA) and C reactive protein (CRP) in cases with hyperlipidemia and their relationship to deficiency or excess syndrome in accord to the differentiation of symptoms and signs in traditional Chinese medicine (TCM). Methods： Three hundred and fifty-three patients with hyperlipidemia were divided into deficiency syndrome(虚证), excess syndrome(实证), and deficiency-excess miscellaneous syndrome(虚实夹杂证) groups. The total cholesterol(TC), triglyceride(TG), low density lipoprotein-cholesterol(LDL-C), high density lipoprotein cholesterol (HDL-C), Glu, UA and CRP in serum were determined and compared among patients with different syndromes and types in TCM. Results： In three syndromes and types of TCM, the changes in TC, TG, LDL-C, HDL-C and CRP were greater in patients with excess syndrome and than those in patients with deficiency-excess miscellaneous syndrome and those in patients with deficiency syndrome. The change of Glu was greater in patients with deficiency syndrome than those in patients with deficiency-excess miscellaneous syndrome and than those in patients with excess syndrome. The change of UA was greater in patients with deficiency syndrome, middle in patients with excess syndrome, and mild in patients with deficiency-excess miscellaneous syndrome. The elevations of TC and TG were slight in deficiency syndrome and moderate in deficiency-excess miscellaneous syndrome, but serious in excess syndrome. Conclusion： The seven indexes of this study are related to different syndromes and types of TCM in hyperlipidemia in different degree. The hyperlipidemia can be distinguished by deficiency syndrome, excess syndrome and deficiency-excess miscellaneous syndrome according to the changes of these indexes. ......
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