黄芪对狗小肠血流量和运动的影响
黄芪,药理学;小肠,药物作用;小肠,血液供给;胃肠活动,药物作用,作者简介,EffectofAstragalusmembranaceusonintestinalbloodflowandmotilityindogs,Subjectheadings,Abstract,AIM,METHODS,RESULTS,CONCLUSION,主题词,摘要,目的,方法,结
湖南中医学院诊断研究所 湖南省长沙市 410007作者简介 李绍芝，男，1953-10-11生，湖南省长沙市人，汉族. 1987年湖南中医学院中医系研究生毕业，1992年赴美国密歇根州立大学生理系进修3年. 副教授，主要从事消化生理的研究，发表论文34篇，主编《中国民间灵验编方》等2部[湖南省长沙市韶山中路119号. 电话(0731) 5556660-794].(收稿 1997-01-26 修回 1997-03-11)
Effect of Astragalus membranaceus on intestinal blood flow and motility in dogs
LI Shao-Zhi, and TAN Xiao-Hong
Institute of Diagnosis, Hunan College of TCM, Changsha 410007, Hunan Province, China
Subject headings Astragalus membranaceus/pharmacology; intestine, small/drug effects; intestine, small/blood supply; gastrointestinal motility/drug effects
Abstract
AIM To study effect of Astragalus membranaceus on intestinal blood flow and motility.
METHODS Different concentrations of Astragalus membranaceus (10%, 30% and 50%) were placed into intestinal lumen of 10 healthy mongrel dogs to observe their effects on intestinal blood flow and motility using electromagnetic flowmeter and pressure transducer, and compared with normal saline.
RESULTS Astragalus membranaceus significantly or very significantly increased intestinal blood flow (ml·min-1·100-1) to 54.85±11.86～73.55±12.40, compared with 42.56±9.34～43.15±10.23 of normal saline (P<0.05 or <0.01), significantly enhanced intestinal muscular tension (kPa) to 0.70±0.27～0.95±0.39, compared with 0.44±0.21～0.51±0.22 of normal saline (P<0.05), and significantly raised intestinal motility amplitude (mv) to 10.53±2.37～12.04±3.37, compared with 6.25±2.31～6.44±2.18 of normal saline (P<0.05). The effect varied among different concentrations of Astragalus membranaceus on digestive function of intestine. ......
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