基因，p53;基因，抑制，肿瘤;胃肿瘤

肿瘤抑制基因p53及p16与胃癌生物学行为的关系

http://www.100md.com 1997年12月15日《世界华人消化杂志》 1997年第12期

基因，p53;基因，抑制，肿瘤;胃肿瘤,病理学;基因表达,作者简介,Correlationbetweenalterationoftumorsuppressorgenep53,p16andbiologicalbehaviorofgastriccancer,Subjectheadings,Abstract,AIM,METHODS,RESULTS,CONCLUSION

     河南医科大学 ¹第一附属医院消化内科 ²实验中心癌症研究室河南省郑州市 450052

    作者简介 邹建湘，男，湖南省湘乡市人，汉族. 1987年空军医学高等专科学校毕业，1994年于河南医科大学获得内科消化硕士学位，同年就读河医大癌症研究室攻读博士学位，从事消化道肿瘤分子学基础的实验与临床研究，已发表论文15篇[郑州市大学路40号. 电话(0371)5968342-5062].(收稿 1997-04-17)

    Correlation between alteration of tumor suppressor gene p53, p16 and biological behavior of gastric cancer

    ZOU Jian-Xiang^1,2, CHEN Yu-Long¹, WANG Zhi-Hui¹, WANG Li-Dong², ZHOU Qi² and ZHAO Xin²

    ¹Department of Gastroenterology, The First Affiliated Hospital, 2Laboratory for Cancer Research, Medical Experimental Center,Henan Medical University, Zhengzhou 450052, Henan Province, China

    Subject headings genes, p53; genes, suppressor, tumor; stomach neoplasms/pathology; gene expression

    Abstract

    AIM To study the correlation between abnormality of tumor suppressor gene p53, p16 and biological behavior of gastric cancer.

    METHODS P53 and P16 protein expressions of 58 cases of primary gastric cancer (38 males, 20 females, aged from 37 to 76 years) were detected by the immunohistochemical methods (ABC). All samples were freshly obtained and immediately fixed with 850g/L ethanol, embedded with paraffin and setioned serially. ......

百拇医药网 http://www.100md.com/html/DirDu/1997/12/15/69/53/20.htm

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