烧伤_代谢;胃_代谢;一氧化氮_代谢;氨基酸氧化还原酶类

烧伤大鼠胃组织一氧化氮及一氧化氮合酶的变化

http://www.100md.com 1997年12月15日《世界华人消化杂志》 1997年第12期

烧伤,代谢;胃,代谢;一氧化氮,代谢;氨基酸氧化还原酶类,代谢;疾病模型，动物,作者简介,Alterationsofnitricoxidesynthaseandnitricoxideingastrictissuesofburnedrats,Subjectheadings,Abstract,AIM,METHODS,RESULTS,CONCLUS

     ¹第三军医大学西南医院烧伤研究所重庆市 400038

    ²解放军264医院烧伤科山西省太原市 030001

    作者简介彭曦，男，1968-10-21生，四川省成都市人，汉族. 1990年第三军医大学本科毕业，1996年第三军医大学硕士研究生毕业，主治医师，博士研究生，主要从事烧伤营养代谢及消化道神经解剖和神经生理的研究，发表论文5篇

    [重庆市高滩岩正街1号. 电话(023)68753497].(收稿 1997-06-18)

    Alterations of nitric oxide synthase and nitric oxide in gastric tissues of burned rats

    PENG Xi¹, FENG Jin-Bin², WANG Shi-Liang², YOU Zhong-Yi¹ and LI Ao¹

    ¹Institute of Burn Research, Southwest Hospital, The Third Military Medical University, Chongqing 400038, China

    ²Department of Burns, Chinese PLA 264 Hospital, Taiyuan 030001, Shanxi Province, China

    Subject headings burns/metabolism; stomach/metabolism; nitric oxide/metabolism; amino acid oxidoreductases/metabolism;

    disease models, animal

    Abstract

    AIM To investigate the regularity of changes of nitric oxide (NO) and two types of nitric oxide synthase (NOS) in gastric tissues after burn injury.

    METHODS Wistar rats (n=64) with 30% TBSA full thickness burns were used as models. The activity of inducible NOS(iNOS) and constitutes NOS (cNOS) as well as the content of NO in gastric tissues were determined at 1, 3, 6, 12, 24, 48 and 72 postburn hour (PBH). Meanwhile, the content of NO and the activity of two types of NOS were analysed by correlation analysis. ......

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