急性肝坏死大鼠NO水平的动态变化和作用
一氧化氮,分析;肝疾病,病理学;精氨酸,分析;疾病模型，动物,项目负责人,Correspondenceto,Dynamicchangesandroleofnitricoxideinratswithfulmianthepatitis,,Abstract,,AIM,METHODS,RESULTS,CONCLUSION,Subjectheadings,摘要,目的
上海第二医科大学附属瑞金医院传染科 上海市 200025王斌，男，1970-04-05，安徽省泗县人，汉族. 1996年上海第二医科大学硕士研究生毕业，博士生.
项目负责人 王斌，200025，上海第二医科大学附属瑞金医院传染科，上海市瑞金二路197号.
Correspondence to Bin Wang, Department of Infectious Diseases, Affiliated Ruijin Hospital, Shanghai Second Medical University,197 Ruijin Erlu, Shanghai 200025, China
Tel. +86·12·64370045-3720
收稿日期 1998-03-08
Dynamic changes and role of nitric oxide in rats with fulmiant hepatitis
Bin Wang, Hong Yu and Xia-Qiu Zhou
Department of Infectious Diseases, Affiliated Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China
Abstract
AIM To study dynamic changes and possible role of serum NO levels in rats with fulminant hepatitis (FH).
METHODS By promoting or inhibiting the synthesis of NO in FH rats models with chemicals, we have detected the changes of serum NO, ALT and AST levels and observed pathological changes of hepatic tissue.
RESULTS ①At 6, 12, 24, 48h, serum NO levels of rat FH models increased significantly compared with normal rat (NO, μmol/L, 90±13 ......
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