肝细胞癌P53,Bcl-2蛋白的表达和细胞凋亡
肝肿瘤;细胞凋亡;P53蛋白;Bcl-2蛋白;免疫组织化学,*美国中华医学基金会(CMB)部分资助,GrantNo.93-582.,项目负责人,*SupportedbytheChinaMedicalBoard(CMB)ofNewYork,GrantNo.93-582.,,Correspondenceto,Apoptosis,Bcl-2andP53proteinex
中山医科大学附属第三医院传染科 广东省广州市 510630彭晓谋,男,1963-10-28生,湖南省茶陵县人,汉族. 1985年湖南医科大学本科毕业,1988年湖南医科大学硕士,1996年中山医科大学博士,讲师,主要从事病毒性肝炎的实验研究工作,发表论文13篇.
*美国中华医学基金会(CMB)部分资助,Grant No.93-582.
项目负责人 彭晓谋,510630,中山医科大学附属第三医院传染科,广东省广州市石牌岗顶.
*Supported by the China Medical Board (CMB) of New York, Grant No.93-582.
Correspondence to Dr. Xiao-Mou Peng, Department of Infectious Diseases, Third Affiliated Hospital, Sun Yat-Sen University of Medical Sciences, Guangzhou 510630, Guangdong Province, China
Tel. +86·20·85516867, Fax. +86·20·87536401
收稿日期 1998-06-06
Apoptosis, Bcl-2 and P53 protein expressions in tissues from hepatocellular carcinoma*
Xiao-Mou Peng, Wen-Wei Peng, Qing Chen and Ji-Lu Yao
Department of Infectious Diseases, Third Affiliated Hospital, Sun Yat-Sen University of Medical Sciences, Guangzhou 510630, Guangdong Province, China
Abstract
AIM To investigate apoptosis in HCC, and its relation to the expression of Bcl-2 and P53 protein.
METHODS In situ method was used to detect apoptosis. IHC was used to detect the expression of Bcl-2 and P53 proteins. Double staining was used to demonstrate the relationship between apoptosis and the expression of Bcl-2 or P53 protein. ......
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