多原发大肠癌微卫星不稳定性的研究
结直肠肿瘤;肿瘤,多原发性;微卫星不稳定性,项目负责人,Correspondenceto,Microsatelliteinstabilityinmultipleprimarycolorectalcancers,,Abstract,AIM,METHODS,RESULTS,CONCLUSION,Subjectheadings,摘要,目的,方法,结果,结论,主题词
第一军医大学南方医院全军消化病研究所 广东省广州市 510515项目负责人 张立力,510515,广东省广州市,第一军医大学南方医院全军消化病研究所.
Correspondence to Li-Li Zhang, Nanfang Hospital, Chinese PLA Institute of Digestive Diseases, First Military Medical University, Guangzhou 510515, Guangdong Province, China
收稿日期 1998-11-21
Microsatellite instability in multiple primary colorectal cancers
Li-Li Zhang, Zhen-Shu Zhang, Ya-Li Zhang, Bao-Ping Wu, Wen Guo, Xiao-Xia Liu and Dian-Yuan Zhou
Nanfang Hospital, Chinese PLA Institute of Digestive Diseases, First Military Medical University, Guangzhou 510515,Guangdong Province, China
Abstract
AIM To study the changeable patterns of microsatellite instability (MSI) in multiple primary colorectal carcinomas (MPCC) and solitary colorectal tumors.
METHODS Silver staining single strand conformation polymorphism-polymerize chain reaction (PCR-SSCP) was used to screen MSI markers at 4 loci on chromosome 2, 5 and 17 in paraffin-embedded tissues of MPCC (n=24) and solitary colorectal tumors (n=21). ......
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