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丁型肝炎患者肝组织中Fas/FasL和肝细胞凋亡表达
http://www.100md.com 2000年1月15日 《世界华人消化杂志》 2000年第1期
肝炎,丁型;细胞凋亡;肝,项目负责人,Correspondenceto,ExpressionofhepatocyteapoptosisandFas,FasLinlivertissuesofpatientswithhepatitisD,,Abstract,AIM,METHODS,RESULTS,CONCLUSION,Subjectheadings,摘要,目的,方法,结果
     中国人民解放军第三军医大学附属西南医院全军传染病专科中心 重庆市 400038

    顾小红,女,1968-06-10生,四川省绵阳市人,汉族. 1988年泸州医学院本科毕业(五年制),1999年第三军医大学硕士研究生毕业,现任主治医师,主要从事病毒性肝炎的研究.

    项目负责人
顾小红,400038,重庆市,中国人民解放军第三军医大学附属西南医院全军传染病专科中心.

    Correspondence to Xiao-Hong Gu, Infectious Disease Center, Southwest Hospital, Third Military Medical University,Chongqing 400038, China

    Tel. +86-23-68757324

    收稿日期 1999-10-25 接收日期 1999-11-28

    Expression of hepatocyte apoptosis and Fas/FasL in liver tissues of patients with hepatitis D

    Xiao-Hong Gu, Qi-Fen Li and Yu-Ming Wang

    Infectious Disease Center, Southwest Hospital, The Third Military Medical University, Chongqing 400038, China

    Abstract

    AIM To study the role of hepatocyte apoptosis and Fas/FasL in pathogenesis of hepatitis D.

    METHODS Expression of HDAg, Fas, FasL and hepatocyte apoptosis in liver specimens of 79 patients with hepatitis D were studied by immunohistochemistry and terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) technique. The relationship between expression of HDAg and expression of Fas/FasL and hepatocyte apoptosis in liver specimens of patients were studied by double stainings and serial sections. ......

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