小鼠实验性自身免疫性肝炎的动态观察
肝炎,免疫学;实验性自身免疫性肝炎;血清诊断;小鼠;自身免疫疾病;自身抗原,项目负责人,Correspondenceto,Dynamicobservationofexperimentalautoimmunehepatitisinmice,,Abstract,AIM,METHODS,RESULTS,CONCLUSION,Subjectheadings
上海第二医科大学附属仁济医院 上海市消化疾病研究所 上海市 200001马雄,男,1968-08-27生,汉族. 医学博士,主治医师. 主要从事慢性肝病的诊治研究. 发表论文10篇,共同主编专著1部,主编助理1部,参编5部,参译1部.
项目负责人 马雄,200001,上海第二医科大学附属仁济医院 上海市消化疾病研究所.
Shanghai Institute of Digestive Disease, Renji Hospital, Shanghai Second Medical University, Shanghai 200001, China
Correspondence to Xiong Ma, Shanghai Institute of Digestive Disease, Renji Hospital, Shanghai Second Medical University, Shanghai 200001, China
Tel. 0086-21-63260930 Ext.2213
Email. xiongma@netease.com
Received 2000-07-17 Accepted 2000-07-21
Dynamic observation of experimental autoimmune hepatitis in mice
Xiong Ma, De-Kai Qiu, Yan-Shen Peng, En-Ling Li and Xiao-Yu Chen
Abstract
AIM To set up and to observe dynamically the murine model of experimental autoimmune hepatitis.
METHODS The syngeneic S-100 antigen emulsified in complete Freud's adjuvant was injected intraperitoneally twice, serum alanine aminotransferase level and histological grade were observed dynamically. We separated S-100 antigen using a 90cm CL-6B sepharose column and observed the T-cell proliferation. ......
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