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HLA-DR抗原和HSP70在肝细胞癌中的表达意义
http://www.100md.com 2001年10月15日 《世界华人消化杂志》 2001年第10期
肝肿瘤,代谢;癌,肝细胞,代谢;HLA-DR抗原,生物合成;热休克蛋白质类70,生物合成;免疫组织化学,项目负责人,ExpressionsignificanceofHLA-DRantigenandheatshockprotein70inhepatocellularcarcinoma,Correspondenceto:,Abstract,AIM,MET
     第三军医大学西南医院全军感染病研究所 重庆市 400038

    蒋业贵,男,1966生,安徽省巢湖市人,汉族,1996年第三军医大学项士,1 999年第三军医大学博士,主要从事病毒性肝炎和肝癌的研究,发表论文15篇.

    项目负责人 蒋业贵,400038 重庆市,第三军医大学西南医 院全军感染病研究所

    Telephone:0086-23-68754141 Fax:0086-23-68754479

    收稿日期 2001-06-12 接受日期 2001-06-12

    Expression significance of HLA-DR antigen and heat shock protein 70 i n hepatocellular carcinoma

    
Ye-Gui Jiang, Yu-Ming Wang and Qi-Fen Li

    Institute of Infectious diseases. Southwest Hospital, Third Military Me dical University, Chongqing 400038, China

    Correspondence to: Ye Gui Jiang, Institute of Infectious disease s.Southwest Hospital, Third Military Medical University, Chongqing 400038, China

    Received 2001-06-12 Accepted 2001-06-12

    Abstract

    AIM
To invetstigate the expression and significance of HLA -DR antigen and heat shock protein70 (HSP70) in hepatocellular carcinoma (HCC).

    METHODS HLA-DR antigen and HSP70 were determined in specimens of 44 cases of HCC and tumor-surrounding tissues by immunohistochemistry.

    RESULTS HLA-DR antigen was not detected in hepatocytes tumor- surrounding tissues. The positive rates of HLA-DR antigen was 43% in tumor cel ls of HCC. The positive rate of HSP70 in HCC was higher than that in tumor-surr ounding tissues (68% vs 27% ......

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