胃癌增生凋亡与调节基因的表达
Proliferation,apoptosisandexpressionofP53andBcl-2ingastriccarcinoma,Abstract,摘要,目的,:,方法,结果,结论,0,引言,1材料和方法,1.1材料,1.2,2结果,2.1胃癌增生和凋亡,2.2胃癌P53和Bcl-2表达,3讨论,4参考文献
潘传敬,刘宽宇,中国人民解放军成都军区总医院病理科 四川省成都市 610083潘传敬,男,1945-12-18生,四川省达州市人,汉族.1970年华西医科大学医学系本科毕业,1982年第三军医大学硕士,主任医师,主要从事肿瘤的病理诊断和癌前病变的研究,发表论文58篇.
项目负责人:潘传敬,610083,四川省成都市,中国人民解放军成都军区总医院病理科. kent120@ etang. com.
电话:028-86570457 传真:028-86570480
收稿日期:2002-07-16 接受日期:2002-07-31
Proliferation/apoptosis and expression of P53 and Bcl-2 in gastriccarcinoma
Chuan-Jing Pan, Kuan-Yu Liu
Chuan-JingPan, Kuan-Yu Liu, Department of Pathology, Chinese PLA General Hospital ofChengdu Commad Area, Chengdu 610083, Sichuan Province, China
Correspondence to: Chuan-Jing Pan, Department of Pathology, Chinese PLAGeneral Hospital of Chengdu Commad Area, Chengdu 610083, Sichuan Province,China. kent120@ etang. com.
Received:2002-07-16 Accepted:2002-07-31
AbstractAIM:To study proliferation and apoptosis in gastric carcinoma (GC) andprecancerous lesions and expression of their regulating genes.
METHODS:Total24 cases of GC, 14 dysplasia (DP), 24 chronic gastritis (10 superficalgastritis, SG, 14 atrophic gastritis, AG) and 32 intestinal metaplasia(IM) were studied by histopathological, immunohistochemical techniqueswith Ki67, P53 and Bcl-2 antibodies, and by TUNEL for apoptosis.Proliferation index (PI), apoptosis index (AI), apoptosis/ proliferationratio, apoptosis degree and positive percent of P53 and Bcl-2 werecounted. ......
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