严重烧伤病人早期血浆内皮素变化与心肌损害关系的初步探讨
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内皮素；肌酸激酶同工酶；严重烧伤；心肌损害,钟克勤马恩庆钟克勤马恩庆
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钟克勤 马恩庆 钟克勤 马恩庆
摘 要：目的：探讨血浆内皮素(ET)变化与烧伤早期心肌损害的关系。方法：采用放免法检测5例严重烧伤病人烧伤早期血浆ET和ASCA仪测定血浆肌酸激酶同工酶(CK-MB)。结果：伤后12h血浆ET(106.0±1.6pg/ml，n=5)较正常人组(47.6±3.4pg/ml，n=8)明显升高。血浆CK-MB在伤后明显升高。相关分析显示，ET升高与CK-MB呈高度正相关。结论：血浆ET升高可能参与了烧伤早期的心肌损害。
关键词：内皮素；肌酸激酶同工酶；严重烧伤；心肌损害
分类号：R644；R363 文献标识码：A
文章编号：1001-0726(2001)01-0042-03
A Preliminary Study of the Relationship between Plasma Endothelin Level and Myocardial Damage at the Early Stage of Severe Burn
ZHONG Ke-qin(Dept. of Burn and Plastic surgery, Xiangya Hospital, Medical College of Central-South University, Changsha, Hunan 410008)
MA En-qing(Dept. of Burn and Plastic surgery, Xiangya Hospital, Medical College of Central-South University, Changsha, Hunan 410008)
ZHONG Ke-qin(Dept. of Burn and Plastic surgery, Xiangya Hospital, Medical College of Central-South University, Changsha, Hunan 410008)
MA En-qing(Dept. of Burn and Plastic surgery, Xiangya Hospital, Medical College of Central-South University, Changsha, Hunan 410008)
Abstract：Objective: To study the effect of plasma endothelin (ET) level on myocardial injury of severely burned patients. Method: Plasma ET level was determined by radio-immunoassay and plasma levels of CK-MB by automatic serum biochemical assay. Result: Plasma ET level increased significantly 12 hr post burn as compared with normal persons (P<0 ......
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