【摘要】 目的 观察立普妥(阿托法他汀)治疗冠心病患者C-反应蛋白的变化，以了解立普妥的非调脂作用。方法 85例冠心病患者随机分成常规治疗组(未服任何调脂药，41例)，立普妥治疗组(服立普妥10mg/d，44例)，测定治疗前后C-反应蛋白(CRP)及胆固醇(TC)，甘油三酯(TG)，低密度脂蛋白(LDL-C)的变化。结果 治疗组治疗前后CRP及血脂各组成分差异均有统计学意义。结论 在冠心病治疗中，使用立普妥治疗，除可明显降低血脂水平外，还可明显降低CRP水平，从而有利于减轻动脉硬化。

    关键词 立普妥 CRP 冠心病 血脂

    The observation of Lipitor’s effect on CRP of CHD

    Huang Chengguo，Zhu Yifan

    The People’s Hospital of Guizhou Province，Guiyang550002.

    【Abstract】 Objective To investigate the action of irregulating lipoprotein through observing the change of C-reactive protein in coronary artery disease patients cured by Lipitor.Methods 85CHD patients were randomly diˉvided into two groups.Group1(normal treatment group)consisted of41patients who administered no drug to regulate lipo.Group2(Lipitor treatment group)consisted of44patients who took at a dose of10mg daily.Compared the differˉences between data obtained before the patients received treatment and data got after treatment in CRP ......