【摘要】 目的 评价卵园孔未闭(PFO)封堵材料(Amplatzer)对心功能的影响。方法 应用组织多普勒成像技术(TDI)对25例PFO病人术前术后的心肌运动进行观察并比较。经心尖四腔位切面，分别获取术前1天和术后1天二尖瓣环侧壁，房间隔瓣环壁，房间隔顶部及三尖瓣环侧壁收缩及舒张运动速度峰值。结果 房间隔瓣环壁及顶部的舒张早期峰值E值在封堵后明显下降(p<0.05)，二尖瓣三尖瓣环的各项收缩舒张指标及房间隔瓣环壁及顶部收缩期指标均无明显改变。结论 Amplatzer封堵PFO对房间隔的舒张运动有影响，对左右心室功能无影响。

    Wang Ji，Huang Feiqiong，Ewert.P，et al.

    Beijing Children’s Hospital Affiliated Capital Medical University，100000.

    【Abstract】 Objective To evaluate the cardiac function in patients with PFO before and after interventional treatment.Methods Tissue Doppler imaging(TDI)was used to determine and compare the movement of myocardial before and after intervention treatment.Diastolic velocity and systolic velocity from the mitral annulus，tricuspid annuˉlus，septal annulus and roof of atrial septumwere obtained in the apical four-chamber view1day before and after inˉtervention.Results The Em of septal motion velocities were lower after than before trancatheter closure.Other paˉrameters of mitral annulus，tricuspid annulus and systolic parameters of septal annulus and roof of atrial septum showed no significant changes between pre-and post-intervention treatment.Conclusion Transcathetre closure of PFO procedure does not affect the left ventricular and right ventricular function ......