【摘要】 目的 观察胸腺肽肠溶片(迪赛片)联合α-2b干扰素(安福隆)对慢性乙型肝炎的治疗效果。方法 选取2002年1～12月西安交通大学第二医院门诊及商州市中心医院感染科门诊确诊为慢性乙型肝炎中度或轻度患者68例，随机分为两组。干扰素组仅肌注干扰素3mu，每日1次，治疗1年;联合治疗组同时口服胸腺肽肠溶片30mg，每日1次，疗程6个月。治疗期间及治疗结束后分别检测指标ALT、HBeAg、HBV DNA定量，结果行χ 2 检验。结果 胸腺肽肠溶片联合干扰素治疗组ALT复常率、HBV DNA恢复正常率及HBeAg阴转率分别为84.84%、60.61%、63.64%。而单用干扰素组相对较低，分别为61.29%、35.48%、38.71%，差异有显著性。结论 胸腺肽肠溶片联合α-2b干扰素治疗慢性乙型肝炎比单用α-2b干扰素治疗慢性乙型肝炎更方便、安全，更有效，值得临床推广应用。

    To study efficacy of thymic polypeptide tablet(TP)combined withα-2b interferon(α-2bIFN)in patients with chronic hepatitis B

    Dang Shuangsuo，Li Shunliang，Zhang Zhengguo，et al.

    Department of Infection，No2Hospital，Xi’an Jiao Tong University，Xi’an710004.

    【Abstract】 Objective To study efficacy of thymic polypeptide tablet(TP)combined withα-2b interferon(α-2bIFN)in patients with chronic hepatitis B.Methods 68patients with chronic hepatitis B were randomly divided into2groups.One group was givenα-2b IFN for one year.The other group received TP for6months as well asα-2b IFN for one year.ALT ......