【摘要】 目的 研究胃肠道肿瘤术后腹腔化疗较之传统静脉全身化疗的优势。方法 比较6年来胃肠道恶性肿瘤患者根治术后行腹腔化疗(86名)和静脉化疗(81名)的复发率，生存率的差异。结果 腹腔化疗组患者1、2、3年无瘤生存率分别为83.6%、75.4%和71.1%，疗效明显优于静脉化疗组的1、2、3年无瘤生存率69.1%、56.8%和46.9%(P<0.05)，两组肿瘤3年腹腔内复发率分别为21.2%和43.2%，差异具有显著性(P<0.01)。结论 作为胃肠道恶性肿瘤根治术后辅助化疗方法，腹腔化疗优于静脉全身化疗，对于减少腹腔内复发有显著效果。

    关键词 胃肠道 恶性肿瘤 腹腔化疗

    Intraperitoneal chemotherapy for gastrointestinal cancer，A clinical research.

    Wang Tianxiang，Yuan Jianming，Jin Zhiming，et al.

    Ruijin Hospital Affiliated to Shanghai Second Medical University，Shanghai200020.

    【Abstract】 Objective To investigate the benefit ofintraperitonealchemotherapy(IPCT)compared to intraˉvenous chemotherapy(IVCT)after curative operation for malignant diseases of gastrointestinal system.Methods Data of167cases of advanced gastrointestinal cancer after curative operation fromMay1998to Dec2003were reviewed.86cases underwent intraperitoneal Chemotherapy.The rest underwent intravenous chemotherapy.The recrudescence rate，survival rate were evaluated.Results In the IPCTgroup ......