【摘要】 目的 观察重度妊娠高血压综合征(PIH)患者血浆中线粒体偶联因子6(CF6)含量的变化，以探讨CF6在其发病中的意义。方法 放射免疫分析法检测血浆CF6的含量(pg/ml)。结果 正常妊娠晚期血浆CF6含量为(226.89±44.07)pg/ml，重度PIH患者为(297.9±68.23)pg/ml，与正常妊娠晚期比较明显升高(P<0.05)。结论 重度PIH患者血浆CF6含量明显升高，提示CF6可能在其病理生理过程中发挥重要的作用，对于变化的机制及其意义有待于深入研究。

    severe pregnancy induced hypertension

    Wang Jurong，Yan Hua，Yin Guiran，et al.

    Department of Obstetrics and Gynecology，Handan Central Hospital，Handan056001.

    【Abstract】 Objective To study the changes of coupling factor6(CF6)level in severe pregnancy induced hyperˉtension.Methods The plasma CF6level was determined by radioimmunoassay for human CF6.Twenty third-trimester pregnantwomen and twenty-one severe pregnancy induced hypertension were enrolled for this study.Results The plasma CF6in third-trimester pregnant women was(226.89±44.07)pg/ml ......