【摘要】 目的 观察萘酚喹治疗恶性疟的临床疗效。方法 以显微镜血检恶性疟原虫阳性病人为观察对象，药物为萘酚喹，成人总量1000mg，首次600mg，24h服400mg，服药后按时测量体温和血检原虫，随访28天，观察治疗效果。结果 萘酚喹治疗恶性疟104例，平均退热时间为(37.6±18.4)h，原虫转阴时间为(66.7±19.16)h，治愈率为100%。药后无明显不良反应。结论 萘酚喹治疗恶性疟疾具有良好的效果。

    关键词 萘酚喹 恶性疟

    Shan Chengqi，Zhang Min，Jiao Xiuqing

    Institute of Microbiology and Epidemiolohy of academy for Military Medicine Science，Beijing100071.

    【Abstract】 Objective To observe the clinical therapeutic efficacies of naphthoquine in patients with falc iˉparum malaria.Methods Patients with Plasmodium falciprumwere selected as the subjects，treated with a single dose of naphthoquine(1000mg)and followed up in preselective time by blood and temperature examination for28days after drug administration.Results 104patients with falciprum malaria were treated and followed up.The mean fever clearˉance time was37.6±18.4hours;the mean parasite clearance time was66.7±19.6hours.The cure rate was100%.No apparent side effect was observed.Conclusion Naphthoquine is effective for the treatment of patients with falciˉparum malaria. ......