【摘要】 目的 探讨大剂量熊去胆酸治疗急、慢性黄疸型肝炎的临床疗效和安全性。方法 73例患者随机分为治疗组(37例)和对照组(36例)，治疗组用熊去氧胆酸，其他保肝药物与对照组相同，疗程4周。结果 治疗组显效率86%，对照组显效率63%，两组比较差异有显著性(P<0.05)，治疗组治疗后的TBIL、DBIL、ALT均比对照组低，差异均有显著性。结论 大剂量熊去氧胆酸联合其他保肝药物治疗急、慢性黄疸型肝炎疗效好，无明显不良反应。

    关键词 熊去氧胆酸 急 慢性黄疸性肝炎

    Effect of high dose ursodeoxycholic acid in the treatment of acute or chronic icteric type hepatitis

    Liu Xing，Ding Chunfeng

    Department of Infection Diseases，The People’s Hospital of Siyang，Jiangsu223700.

    【Abstract】 Objective To observe the clinical efficacy and safety of ursodeoxycholic acid in the treatment of acute or chronic icteric type hepatitis.Methods Seventy-three patients were randomly divided into treatment group(37cases)and control group(36cases).Two groups took the same liver protecting drugs for four weeks and ursodeoxyˉcholic acid for treatment group.Results The significant effective rate was86%in treatment group ......