【摘要】 目的 研究超细三七粉胶囊作为保健食品的安全性。方法 通过急性毒性试验，Ames试验，小鼠骨髓微核试验，小鼠精子畸形试验、30天喂养试验，观察超细三七粉胶囊的毒理作用。结果 雌雄大、小鼠急性经口LD 50 >10000mg/kg体重，属无毒级;Ames试验、小鼠骨髓微核试验和精子畸形试验等3项遗传毒性试验结果均为阴性;30天喂养试验未见有明显毒性。结论 超细三七粉胶囊无明显毒性，符合保健食品的安全性要求。

    关键词 超细三七粉 微核 精子畸形 Ames试验

    Toxicological assessment of superfine powder capsule of radix notoginseng

    Cui Xiuming，Ke Jinhu，Zhu Yan，et al.

    Wenshan Prefecture Sanqi Research Institute，Yunnan663000.

    【Abstract】 Objective To evaluate the edible safety of superfine powder of radix notoginseng as health food.Methods Genetic toxicity test、acute toxicity test and thirty days feeding tests were performed.Results The oral LD 50 in mice or rats was greater then10000mg/(kg.bw)and belonged to the nonpoisonous.The negative results were obtained in yenetic toxicity test，including Ames test ......