【摘要】 目的 探讨彩色多普勒对糖尿病下肢动脉病变(LEAD)的诊断价值及有关LEAD的危险因素。方法 对60例糖尿病患者及40例对照组进行下肢动脉超声检测，观察下肢动脉病变与糖尿病的关系，并根据血糖控制好坏进行分组，分析相关危险因素。结果 糖尿病组下肢动脉斑块检出率90%，显著高于对照组72.5%(P<0.05)。糖尿病组下肢动脉斑块形成以膝关节以下动脉为多见，动脉狭窄与闭塞发生率也明显高于对照组(P<0.01)。相关危险因素分析显示糖尿病下肢动脉病变程度与糖尿病病程及总胆固醇无关，与年龄、血糖、糖化血红蛋白、甘油三酯、低密度脂蛋白-胆固醇呈正相关，与高密度脂蛋白-胆固醇呈负相关。结论 下肢动脉超声检查对糖尿病下肢动脉病变的预测有较高的临床价值。LEAD的发生与血糖控制不佳、脂质代谢紊乱有关。

    关键词 彩色多普勒 糖尿病 下肢动脉病变

    An evaluation on the relationship between lower extremity arterial disease and typeⅡDiabetes

    Lu Huihua，Ren Jianying，Li Jiashu

    Central Hospital of Xuhui District，Shanghai200031.

    【Abstract】 Objective To investigate the diagnostic value of colour Doppler in lower extremity arterial disease(LEAD)in diabetic patients and its risk factors.Methods The arteries of bilateral lower extremities in60diabetic patients and40normal controls were examined using colour Doppler to study the relationship between LEAD and diaˉbetes.The patients were divided into2groups according to blood glucose level to study the risk factors of LEAD.Reˉsults The examination indicated that lower extremity atherosclerosis were found in90percent of the diabetes group.This figure is significantly higher than that of the control group ......