【摘要】 目的 探讨紧急冠脉内支架术联合抗凝治疗心脑卒中(HBS)的效果及安全性。方法 共24例HBS患者于入院后随机分为治疗组、对照组。治疗组患者于入院后1h内行冠脉造影及冠脉内支架植入术，随后给予联合抗凝治疗。对照组给予抗凝、脱水、改善心肌供血等常规治疗。观察两组患者的临床治疗效果、并发症发生率、病死率并随访冠脉内支架术联合抗凝对HBS的长期效果。结果 治疗组所有患者冠脉恢复再通，前向血流均达TIMIⅢ级，脑功能亦有不同程度恢复。无严重并发症发生，无继发脑出血，无一例死亡。治疗组病死率显著低于对照组(P<0.01)。结论 紧急冠脉内支架术联合抗凝治疗HBS是安全、可靠的。

    关键词 紧急冠脉支架术 联合抗凝 心脑卒中

    The study of emergent coronary stent implantation associated anticoagulation therapy in heart brain stroke

    Zhang Mingzhe

    Department of Cardiology，The Central Hospital of Shengli Petroleum Administrative Bureau，Dongying257034

    【Abstract】 Objective To evaluate the effect and safety of emergent coronary stent implantation associated antiˉcoagulation therapy in heart brain stroke(HBS).Methods 24patients with HBS were divided into2groups randomly afˉter admission，12patients with HBS in treatment group underwent coronary angiography and coronary stent implantation within1hour after admission，followed by associated anticoagulation therapy.12patients in control group received rouˉtine therapy.We observed success rate of stent implantation，clincal effect，incidence of complications and long-term influcence of associated anticoagulation to HBS.Results All patients in treatment group coronaries were reopened ......