【摘要】 目的 本文从自由基代谢角度探讨了血清SOD与消化性溃疡的关系。方法 放免法测定Cu、Zn-SOD。结果 十二指肠溃疡的血清SOD值显著低于对照组(P<0.01)，胃溃疡、复合性溃疡的血清SOD值亦明显低于对照组(P<0.05)。结论 消化性溃疡的发生系由于SOD活性下降所致。因此提示临床上可采用自由基清除剂来治疗消化性溃疡。

    关键词 消化性溃疡 超氧化物歧化酶(SOD)

    THE change of serum in superoxide，activites content of with peptic ulcer

    Qu Zhiwei，Pang Wei，Li Binxian

    Department of Gastroenterology the Affiliated Hospital of the Bei Hua University，JiLin132011.

    【Abstract】 Objective We conducted relationship between serum of superoxide dismutase activities and pepˉtic ulcer from free radical.Methods Cu、Zn-SOD were determined by radioimmunoassay method.Results The serum of SOD in Duodenal ulcer was significantly lower than that of the control group(P<0.01).SOD in gastric ulcer and combined ulcer was significantly lower than that of the control group(P<0.05).Conclusion We suggest the peptic ulcer of patients should be treated by scavenge the peptic ulcer of patients should be treated by scavenge of free radicals in clinical practice.

    Key words peptic ulcer superoxide dismutase(SOD)

    消化性溃疡的发生机制目前尚不完全清楚 ......