【摘要】 目的 了解吸毒人员中丙型肝炎感染状况及其影响因素，为防治丙型肝炎提供科学依据。 方法 采用现况研究、整群抽样、随机抽取某男性戒毒所和某女性戒毒所中的吸毒者，以问卷的方式收集吸毒人员有关资料并采集血标本。用酶联免疫吸附试验(ELISA法)，检测血清中抗-HCV。采用SPSS11.0软件进行统计分析。 结果 772例吸毒人员中HCV总感染率为85.75%，性别及年龄感染率差异有显著性，不同吸毒方式感染率差异有非常显著性(P<0.001)，注射吸毒者感染率明显高于非注射方式吸毒者。吸毒年限、是否纹身及是否扎耳孔感染率差异均有显著性(P<0.05)。而性行为与感染率差异无显著性(P>0.05)。 结论 丙型肝炎作为血液传播性疾病，在吸毒人员中其感染与性行为相关性不显著，而与共用注射器吸毒、纹身及扎耳孔有密切相关。因此，对吸毒人员进行HCV感染相关知识的宣传教育及危险行为的干预十分重要。

    【关键词】 吸毒人员 丙型肝炎病毒(HCV) 酶联免疫吸附试验 感染率 影响因素

    Hepatitis C virus infection and its affecting factors in drug abusers

    Wang Xiu，Li Dengqing，Huang Minzhu，et al.

    Faculty of Laboratory Medicine，College of Medical Technology and Information，Central South University，Changsha410013.

    【Abstract】 Objective To study the prevalence of hepatitis C virus(HCV)infection in durg abusers and its affecting factors and to offer scientific evidence for preventing and controlling HCV infection.Methods 772serum samples were collected through randomization cluster-sampling from drug abusers.General information was obtained from a questionnaire survey.Anti-HCV antibodywas examined by ELISA kit.The chi-square testwas used for com-parison and all calculations were performed using SPSS11.0.Results The total infection rate of HCV in772drug abusers was85.75%.The infection rate of taking drug by injection was significantly higher than that of the taking drug without injection(46.1%vs93.6%P<0.001).The HCV infection rates were significantly affected by the fol-lowing factors ......