【摘要】 目的 探讨测定血清血小板衍生因子(platelet-derived growth factor，PDGF)水平与卵巢肿瘤诊断及预后的关系。 方法 选择26例卵巢恶性肿瘤(MAN)、32例卵巢良性肿瘤(BEN)患者为2个研究组，24例正常人为对照组(CON)，用酶联免疫吸附法(ELISA)测定各组术前血清的PDGF水平。 结果 (1)MAN组较BEN组及CON组血清PDGF水平升高，组间差异有显著性(P<0.05);BEN组与CON组PDGF水平接近，差异无显著性(P>0.05)。(2)卵巢恶性肿瘤患者中，肿瘤分化差者(G 3 )血清PDGF高于肿瘤分化较好者(G 1 、G 2 )(P<0.05)，晚期卵巢癌患者的血清PDGF水平高于早期患者(P<0.05)。 结论 血清PDGF水平对卵巢肿瘤的诊断及预后有一定价值。

    关键词 卵巢肿瘤 血小板衍生因子

    The detection of serum platelet-derived growth factor in58 patients with ovarian neoplasm

    Yue Jun，Xie Lan，Pu Haiying

    Department of Obstetrics and Gynecology，Sichuan Provincial People's Hospital，Chengdu610072.

    【Abstract】 Objective To detect the levels of the preoperative serum platelet-derived growth factor(PDGF)in patients with ovarian tumor，and to evaluate the correlation between serum PDGF and diagnosis or prognosis of ovar-ian neoplasm.Methods 26patients with malignant ovarian neoplasm(MAN)，32patients with benign ovarian neo-plasm(BEN)were included as two study groups ......