【摘要】 目的 比较诺维苯(NVB)化疗时不同预防用药对局部皮肤及静脉的保护作用。 方法 试验对象分两组，一组患者使用NVB后立即予生理盐水20ml静脉推注(iv)。另一组患者使用NVB前予地塞米松5mg iv，NVB后予生理盐水250ml静脉滴注，所有患者均观察4周。 结果 在NS组中静脉炎及局部皮肤损伤发生率4.44%(2/45)，在DXM组中静脉炎及局部皮肤损伤发生率4.9%(2/41)。两组差异无统计学意义，P=0.674。 结论 地塞米松对静脉和局部皮肤的保护作用不明显。

    【关键词】 地塞米松 预防 静脉炎及皮肤损伤

    【Abstract】 Objective To observation saline or dexasine's protective function to local skin and vein in NVB hemotherapy.Methods The objects were divided into two teams.One team was given saline20ml infusion and the other was given dexasine5mg before NVB infusion and saline250ml infusion immediately after NVB chemotherapy.All patients was observed for4weeks.Outcomes:The mobidity of phlebitis and local skin damage are4.4%and4.9%in saline and dexasine team ......