【摘要】 目的 从肺泡巨噬细胞吞噬指数变化的角度探讨脾切除术对肝硬化门脉高压症(PHT)的肺脏免疫功能影响，评估保脾手术对治疗PHT的优越性。

    方法 对模型大鼠及脾切除后的模型大鼠的肺泡巨噬细胞进行体外细胞培养。

    结果 脾切除术后的大鼠的肺泡巨噬细胞(PAM)的吞噬指数显著低于对照组大鼠(P<0.01)。 结论 在治疗PHT时，从机体免疫角度来说保脾手术可能优于脾全切术。

    【关键词】 肝硬化/门脉高压症 肺泡巨噬细胞 吞噬指数 大鼠

    【文献标识码】 A 【文章编号】 1680-077X(2005)02-0103-02

    Experimental study of phagocytosis index change of alveolar macrophage after and former spleen resection in liver cirrhosis and portal hypertension rats Wang Qiang，Yang Ting，Luo Wei

    Department of General Surgery，Center Hospital of Jiamusi City of Heilongjiang Province，Jiamusi154003.

    【Abstract】 Objective To evaluate the effect of Spleen resection on immunity of lung with hypertension(PHT)from phagocytosis index change of alveolar macrophage.Evaluate the advantage of the operation of preserving spleen.Methods Isolated macrophage in alveolar were cultured after the spleen of model rats were cut.Results The Phagocytosis index of macrophage in alveolar with spleen resection is lower than the rats whose spleen were not cut.Conclusion For the treatment of PHT the operation of preserving spleen is much better than the spleen resection on the immunity of the body. ......