【摘要】 目的 为探讨心肌钙蛋白I(cardiac troponinⅠ，cTnI)在冠心病诊断中的应用价值。 方法 对国内外的近年来主要研究概况进行分析综述。 结果 急性心肌梗死(AMI)患者血清cTnI存在动态变化规律;cTnI与CK-MB、心肌钙蛋白T有一定的诊断相关性，但其漏诊率及误诊率均明显低于后两者;血清cTnI水平判断冠心病患者预后有重要意义。 结论 心肌钙蛋白I是反映心肌细胞损伤坏死的特异性、敏感度高的标志物。

    关键词 心肌钙蛋白I 急性心肌梗死(AMI) 冠心病

    Application of cardiac troponin I(cTnI)in the diagnosis and prognosis of coronary heart disease

    Liao Xiyu

    Department of Physiology，Hunan College of Traditional Chinese Medicine，Changsha410007.

    【Abstract】 Objective To probe into the application of cardiac troponin I(cTnI)in the diagnosis and progno-sis of coronary heart disease(CHD).Methods The major articles domestic and abroad published in recently years were summarized and analyzed.Results There was dynamic metabolic regularity in the serum cTnI of patient suffered acute myocardial infarction.The correlation among cTnI，CK-MB and cTnTwas close in some degree in the diagno-sis，but the application of cTnI decreased the rate of missed diagnosis and misdiagnosis rate and judged the prognosis of CHD.Conclusion cTnI was the hypersensitive and specific designative substance reflecting the cardiac muscle cellular damage. ......