【摘要】 目的 了解降钙素原在小儿全身炎症反应综合征(SIRS)中的变化及其临床意义。 方法 采用快速半定量法(双抗夹心免疫发光法)检测(BRAHMS，Diagnostica，Berlin，Germany)，对62例SIRS患者进行降钙素原(PCT)的测定。 结果 SIRS患者细菌感染者PCT显著升高，有效抗生素治疗后迅速下降，至恢复期接近正常水平;非细菌感染者整个病程中PCT水平升高不明显(P<0.001)。 结论 PCT测定可作为SIRS细菌感染的重要依据，同时也是判断治疗效果的客观依据之一。

    关键词 降钙素原 全身炎症反应综合征 抗生素

    Changes and clinical significance of serum procalcitonin in systemic inflammatory response syndrome

    Chen Fengyi，Wang Leying，Yan Lin，et al.

    Yichang First People's Hospital，Hubei443000

    【Abstract】 Objective To investigate serum procalcitonin(PCT)in patients with systemic inflammatory response syndrome(SIRS).Methods procalcitonin of62patients with SIRS were measured by immunology assay.Results High levels of PCT correlated SIRS bacterial infect rapidly and reached normal levels after antibiotic treatment.But the PCT levels were low in patients with unbacterial infect(P<0.001).Conclusion The measurement of serum PCT might be of value in the bacterial infect with SIRS. ......